A Comparative Study Of The Risk Of Asymptomatic Cerebral Infarction In Patients With Paroxysmal Atrial Fibrillation During Perioperative Period After Cryoballoon And Radiofrequency Ablation

Object:To compare the risk of silent cerebral infarctions caused by Cryoballoon and Radiofrequency ablation in patients with paroxysmal atrial fibrillation.Method:1.Eighty patients with paroxysmal atrial fibrillation were selected from the People’s Hospital of Zhangzhou and the Second Affiliated Hospital of Nanchang University from August 2017 to January 2019.They were divided into two groups,40 in each group.One group underwent cryoballoon ablation(cryoballoon group);the other group underwent radiofrequency ablation(radiofrequency ablation group).2.Baseline data(age,sex,smoking history,drinking history,past medical history,preoperative anticoagulation or antiplatelet drug use,blood lipids,blood glucose,glycosylated hemoglobin,D-dimer,high-sensitivity C-reactive protein,Preoperative head magnetic resonance,echocardiography,CHADS2 score and other indicators).3.Complete MRI and a neurological physical examination within 48 hours after surgery.Primary endpoint: acute asymptomatic cerebral infarction detected by MRI within 48 hours after surgery.Result:1.There were 5 patients(6.25%)with new cerebral infarction,including 2 new cerebral infarction lesions in the cryoballoon group(5%),and 3 new cerebral infarction lesions in the radiofrequency ablation group(7.5).%);there was no statistically significant difference between the two groups(P>0.05).2.There were 7 patients(8.75%)with newly diagnosed intracranial infarction.Among them,3 patients in the cryoballoon group had new cerebral infarctions(7.5%);4 patients in the radiofrequency ablation group had new cerebral infarctions.Lesions(10%);no statistical significance between the two groups(P>0.05).3.There was no statistically significant difference between the patients with new cerebral infarctions and those without cerebral infarctions(P>0.05)..Conclusion:1.Cryoballoon ablation and radiofrequency ablation result in the same risk of asymptomatic cerebral infarction.2.Catheter ablation increases the risk of asymptomatic cerebral infarction in patients.