The Value Of Dual-source CTA In Judging The Coronary Atherosclerotic Plaque

Purpose:(1)To evaluate the diagnostic value of dual source computer tomography angiography in judging the plaque quantity and stability of intermediate lesions with the intravascular ultrasound as the gold standard.(2)Coronary artery CTA examination was performed to evaluate the progression of coronary artery calcification score in suspicious coronary artery heart disease and its relationship to the severity of coronary artery stenosis,and the risk factors related to CACS were analyzed.Methods:(1)62 cases of intermediate lesions confirmed by coronary angiography.To evaluate the value of DSCTA on the quantitative and qualitative analysis of intermediate plaques with IVUS as the gold standard.EEMCSA,MLA,PA,PB,area of narrow rate,EI and RI were analyzed and compared.The sensitivity,specificity,positive predictive value,negative predictive value and accuracy of DSCTA in diagnosing vulnerable plaques were determined and observe the intermediate lesions in coronary vascular distribution roughly.(2)Retrospective analysis of 143 patients with suspicious CHD examined with Coronary artery CTA and Collected the patient basic data.All patients were divided into progression of CACS group and normal CACS group.The annual rate of change of total CACS,progression of CACS group and normal CACS group was Compared.Compared to progression group and non-progression group in the overall coronary artery stenosis.with a baseline calcium buildup of 0,1-99.100-399 and≥400,comparing progression between the CACS progression group and the narrowing of the coronary arteries.COX’s regression was applied to analyse multiple risk factors and the progress of the calcification.Results:(1)There was no significant difference in judging the stenosis rate of intermediate lesions of coronary artery between DSCTA with IVUS.The values of EEMCSA,MLA,PA,PB,EI and RI were not significantly different and the correlation was good between DSCTA with IVUS.DSCTA high diagnostic accuracy of vulnerable plaques.Left anterior descending branch has the highest probability of occurrence.(2)The calcification score in total calcification,progression group and non-progression group were all statistically significant.In progression group,the overall narrow had a tendency to increase at both the patient and vascular levels,it was statistically significant.When baseline calcification score ≥100 in progression group,the overall narrow progression has significance.calcification score progression was closely related to hypertension,lipid and diabetes.Conclusions:(1)DSCTA had a high diagnostic value in both the quantification and the qualitative analysis of intermediate lesions with the intravascular ultrasound as the gold standard and intermediate lesions is most likely to occur in the left anterior descending branch.(2)Coronary artery calcification score had a tendency to develop and progress along with the time.The overall narrow tended to progression at levels both in patients and vascular among the calcification progression group.As patients with baseline calcification score≥100 in calcification progression group,the narrow progression was significantly.The progression in calcification score was associated with hypertension,dyslipidemia and diabetes.