Comparison Of Microwave Ablation And Laparoscopic Hepatectomy In The Treatment Of Hepatic Hemangioma:A Meta-analysis Of Randomized Trials

Aim: The aim of this study was to compare the clinical efficacy of microwave ablation and laparoscopic hepatectomy in the treatment of hepatic hemangioma,and the clinic data of major concern include operation time,operation of bleeding,length of hospitalization,postoperative pain degree and postoperative liver function.Methods: We conducted a comprehensive search of the CNKI,VIP database,Wan Fang database,PubMed,EMBASE,and the Cochrane Library database to identify relevant available articles from their inception to December 2018.Two researchers screened the literature,extracted data and evaluated the literature quality independently according to the inclusion and exclusion criteria.We used RevMan 5.3 software for statistical analysis.Results: Five trials with 399 patients were included.201 patients received microwave ablation and 198 patients received laparoscopic hepatectomy.According to the meta analysis,the microwave ablationgroup was superior to the laparoscopic hepatectomy group in reducing operation time,operation of bleeding and postoperative pain degree,while the liver function of the laparoscopic hepatectomy group was better than microwave ablation group on the first day after surgery.There was no statistical difference in the liver function on the third day after surgery and the length of hospitalization between the two groups.Conclusions:Both microwave ablation and laparoscopic hepatectomy are the treatment options for hepatic hemangioma.Compared with laparoscopic hepatectomy,microwave ablation has shorter operation time,less operation of bleeding and lower postoperative pain degree in patients with hepatic hemangioma,but worse liver function on the first day after surgery.There was no statistical difference in the liver function on the third day after surgery and the length of hospitalization between the two groups.