Comparative Analysis Of Clinical Materials Among 836 Postoperative Thyroid Nodules Patients

Background and Aims: To analyse the clinical materials of 836 postoperative thyroid nodules patients,and to campare the correlation affected by different factors between benign and malignant thyroid.And to evaluate the clinical value of contrast-enhanced ultrasonography(CEUS)in diagnosing thyroid carcinoma.Methods: The clinical data of 836 patients with thyroid nodules,who were operated in Xin Hua hospital between January 2014 and August 2015,were analyzed in order to compare the clinical data,postoperative pathology and thyroid ultrasound.Then compare the diagnostic results of CEUS of 132 thyroid nodules to the postoperative pathologic findings,and to summarize its imaging features.Results: There were 489 benign nodules(58.5%)and 347 malignant nodules(41.5%)among 836 casess.The ratio of benign and malignant thyroid nodules was 1.41:1;By sex group thyroid carcinoma accounts for 46.2% of the men and 39.7% of women.The proportion of thyroid cancer in men is higher than that of women.The average age of benign nodules group was(53.47±12.92)years old,while malignant nodules group was(48.16±13.65)years old.The level of TPOAb and Tg Ab in malignant nodules group is significantly higher than that in the benign group.(P<0.05)There was statistical significance in the difference of the aspect ratio and the boundary between the benign and malignant nodules in thyroid ultrasound examination.The malignant thyroid nodules mainly refered to papillary carcinoma,which was characterized by low enhancement and slow in fast out performance in the contrast-enhanced ultrasound examination.Conclusions:(1).Although the number of female patients is significantly higher than men in thyroid nodules disease,the malignant thyroid nodule rate of men is higher than that of female patients;According to age,the younger patient with thyroid nodules is,the higher incidence of malignant nodules.50 to 59 years old age group is at the peak of the illness.(2).TPOAb,Tg Ab is an important symbol of autoimmune thyroid disease,the incidence of hashimoto’s thyroiditis and thyroid papillary carcinoma has certain relevance to benign and malignant thyroid nodule identification has a certain significance.(3).There was statistical significance in the difference of the aspect ratio and the boundary between the benign and malignant nodules in thyroid ultrasound examination.(4).The contrast-enhanced ultrasound examination in diagnosing thyroid carcinoma has much more specificity and sensitivity,the “low-enhanced" and "slow in fast out" signs for ultrasonic imaging examination were the important imaging features of malignant thyroid nodules.