The Study Of The Correlation Between TCM Syndromes Of Chronic Sinusitis With Nasal Polyps (CRSwNP) And Short-term Effects After Operation

Objective:The purpose of this study is to explore the correlation between different TCM syndromes and the short-term efficacy of CRSwNP combining the respective advantages of Chinese and Western medicine,in order to provide more basis for pre-operative evaluation of CRSwNP,provide more ideas for post-FESS treatment and nursing,and provide objective proofs for the implementation of post-operative TCM prevention and treatment strategies.Methods:71 cases of CRSwNP patients treated with FESS in our hospital were selected from three TCM syndromes:Gallbladder-fu Stagnation-heat syndrome,Spleen-stomachDamp-heatsyndromeandSpleen-QiDeficiency syndrome(2018.3.14-2018.12.19),They were followed up regularly for at least three months.Data of preoperative VAS score,endoscopy score,the CT score,peripheral blood EOS and the 3 months after operation VAS score,endoscopy score and the tissue EOS infiltration ratio were collected.The D-value of VAS average score,endoscopy score and peripheral blood and tissue EOS infiltration of three groups of TCM syndromes after operation were compared and analyzed to explore whether there were differences in TCM syndromes and short-term efficacy of CRSWNP.Results:Among the three TCM syndromes,Spleen-qi Deficiency Type accounted for 36.62%,Spleen-stomach Damp-heat Type accounted for 45.07%,and Gallbladder-fu Stagnation-heat Type accounted for 18.31%.The VAS average score difference,endoscopy score difference and tissue EOS comparison of the three TCM syndromes showed that there were significant differences between the Spleen-qi Deficiency Type and the Gallbladder-fu Stagnation-heat Type and the Spleen-stomach Damp-heat Type(P<0.05),while there was no significant difference between the Gallbladder-fu Stagnation-heat Type and the Spleen-stomach Damp-heat Type(P>0.05).The short-term effects of three TCM syndromes after operation was significantly different(X ~2=17.068,P=0.001,P<0.05).And further comparison,there was no significant difference between Spleen-stomach Damp-heat Type and Gallbladder-fu Stagnation-heat Type and Spleen-qi Deficiency Type(P>0.05).There was significant difference between Gallbladder-fu Stagnation-heat Type and Spleen-qi Deficiency Type(P=0.018,P<0.05).Among them,the short-term effect control rate of Spleen-qi Deficiency Type was the lowest(57.69%).It is suggested that TCM syndromes are correlated with the short-term efficacy of CRSwNP.Conclusion:The uncontrolled rate of short-term efficacy of CRSwNP was 14%.TCM syndromes are one of the influencing factors of CRSwNP’s short-term efficacy,while the Spleen-qi Deficiency Type is the worst.The infiltration degree of tissues EOS of CRSwNP patients with different syndromes was different,the infiltration degree of EOS in tissues with Spleen-qi Deficiency was the highest.