Clinical Observation On Dynamic Changes Of Acupoint Body Surface Temperature In Patients With Knee Osteoarthritis Based On Acupoint Sensitization Theory

Objective:In this study,patients with knee osteoarthritis were used as the target,and the acupoint temperature was used as an observation index.By using clinical epidemiological methods,prospective cohort study is conducted to reveal the spatial distribution differences and dynamic changes of acupoint thermalization in disease states so as to provide reliable evidence for establishing clinical diagnosis and treatment decisions and further develope the traditional meridian and acupoint theory.Methods:This study was conducted in a group of patients with knee osteoarthritis who were 40-80 years old and met the diagnostic criteria for knee osteoarthritis in the 2007 Guidelines for the Diagnosis and Treatment of Osteoarthritis.The healthy subjects were located in the control group.A platform thermal imager called Fotric226 was used for detecting the difference in body surface temperature between the patient and the healthy subject to determine the acupoint heat-sensitive cut-off value and observe the difference between the two groups.A prospective cohort study was conducted with 246 patients diagnosed with KOA as subjects.The acupoint body surface temperature and disease progression were observed.The observation was performed every week and lasted for 4 weeks.To compare the time and spatial variation of acupoint temperature and heatsensitive rate at different time points from the direction of menstruation,location and region.The multi-level statistical analysis model was used to analyze the influencing factors of acupoint temperature sensitization.Results:1.Comparison of temperature differences between patients and healthy people.Acupoint temperature measurement of patients with crane top,Heding(EX-LE2)、Dubi(ST35)、Xuehai(SP10)、Liangqiu(ST34)、Yinlingquan(SP9)、Yanglingquan(GB34)、Xiguan(LR7)、Ququan(LR8)、Zusanli(ST36)、Weiyang(BL39)、Mingmen(GV4)、Yaoyangguan(GV3)、Xuanzhong(GB39)Values are higher than healthy people.2.Results of comparison of differences in heat-sensitive rate between acupuncture points of patients and healthy people.The acupoint heat-sensitization rate of patients was higher than healthy people,and the difference was statistically significant(p<0.05).The sensitization rate of the patient’s Xuanzhong(GB39),Liangqiu(ST34),Mingmen(GV4),Zusanli(ST36)and other points was relatively large.3.Analysis of acupoint temperature sensitization with time in patients with knee osteoarthritis.(1)It was found that there were statistical differences between the four temperature measurements of the lumbar back acupoints Shenshu(BL23),Yaoyangguan(GV3),Mingmen(GV4),and Dazhu(BL11)R.There was no statistical difference between the temperature measurements of the knee joint local acupoints at different time points.(2)It was found that the sensitization rate decreases with the increase of the number of times of measurement,except for the four times temperature sensitization rates of Xuehai(SP10),Heding(EX-LE2)and Dazhu(BL11)R.There was no significant difference in the 4 times of heat-sensitive rate change of acupoints.4.Results of spatial variation analysis of acupoint temperature sensitization in patients with knee osteoarthritis.(1)It was found that the temperature at the four time points of the Footyangming(stomach)meridians and the Foot-taiyang(bladder)meridians were higher than that of the Foot-shaoyang(Gallbladder)meridians and Foot-sanyin meridians acupoints.After comparing the temperature sensitization rates at different time points in different meridians.It was found that the four sensitization rates of the Footyangming(stomach)meridians were higher.The four sensitization rates of the Footshaoyang(Gallbladder)meridians were lower.(2)It was found that the four sensitization rates of local acupoints were higher.The four sensitization rates of distal acupoints and lumbar back were relatively low,but both are greater than 60%.Conclusions:1.KOA patients are characterized by an increase in infrared temperature,and acupoint heat-sensing phenomenon is common.2.There is a time-changing regularity of acupoint heat-sensing in patients with knee osteoarthritis.The changes of acupoints in the waist and back of KOA patients are significantly different from those in local acupoints.Acupoint temperature changes tend to be stable.3.KOA patients have a high temperature zone in the acupoints of the Footyangming(stomach)meridians and the Foot-taiyang(bladder)meridians,and the heatsensing phenomenon has a correlative relationship with meridians.4.The local acupoint temperature sensitization rate of KOA patients is high,and the distribution of heat-sensitive acupoints has regional characteristics.5.There is a correlation between the thermodynamic changes of the acupoints in KOA patients and the disease state.The temperature sensitization rate of acupoints is related to time,age,gender,disease course and Womac score.