Study On The Relationship Between Body Mass Index And Waist Circumference Of Middle-aged And Elderly People And Incidence Diabetes

Objective:To analyze the relationship between body mass index,waist circumference and the incidence of diabetes mellitus in middle-aged and elderly people,and to explore the predictive effects of the two indexes on the onset of diabetes mellitus.Methods:In August 2008,a natural population aged 40-79 years old in Caichang Town,Dayi County,Chengdu City was selected as the survey object.The general data and related medical history of the subjects were collected.Blood pressure,height,weight,waist circumference were measured,and blood glucose,blood lipid profiles and uric acid were detected.597 non-diabetic patients were screened out through diabetes history,fasting blood glucose and oral glucose tolerance test 2-hour blood glucose.The population was followed up in February 2018.The end point of follow-up was diabetes.A total of 487 people(81.6%)were followed up,excluding body mass index<18.5kg/m~2(17cases),and 470 subjects were finally included in the study.At baseline,the patients were divided into 40-49 years old group,50-59 years old group and≥60 years old group,and diabetes incidence was divided into diabetes group and non-diabetes group.Variance analysis of repeated measurement data was used to compare the differences of body mass index and waist circumference between diabetes group and non-diabetes group.Logistic regression was used to analyze the relationship between baseline body mass index and waist circumference and the onset of diabetes,and receiver operating characteristic curve was used to analyze and compare the predictive effects of body mass index and waist circumference on the onset of diabetes.Results:1.Among 470 subjects surveyed,there were 84 new-onset diabetes patients,with an incidence rate of 17.9%.The baseline age,body mass index,waist circumference,systolic blood pressure,diastolic blood pressure,uric acid and triglyceride in diabetes group were higher than those in non-diabetes group,and the difference was statistically significant(P<0.05).At baseline,there was no significant difference in the proportion of patients with diabetes family history,sex,smoking rate,alcohol consumption rate,high density lipoprotein cholesterol,low density lipoprotein cholesterol and total cholesterol between the two groups(P>0.05).2.There were statistical differences in body mass index and waist circumference between baseline and follow-up(P<0.05),while there were no statistical differences in body mass index and waist circumference between diabetes group and non-diabetes group(P>0.05).3.Multivariate Logistics regression results showed that body mass index and waist circumference were both risk factors for the onset of diabetes..4.The area under curve(95%CI)of body mass index and waist circumference for predicting the onset of diabetes were 0.600(0.536~0.664)and0.605(0.539~0.670),respectively.There was no statistical difference between the areas under curve of the two indexes for predicting the onset of diabetes(P>0.05).Conclusion:Body mass index and waist circumference of the middle-aged and elderly people in Chengdu rural areas have certain predictive effects on the onset of diabetes,and the predictive effects are similar.The two indicators are equally important for the prevention of diabetes in the middle-aged and elderly people in Chengdu rural areas,and the monitoring of the two indicators should be strengthened.