Correlation Between PR Interval And Prognosis Of Cardiac Resynchronization Therapy In Patients With Heart Failure

Objective To analyze whether there is a correlation between the baseline PR interval in the surface electrocardiogram and the outcome of patients after cardiac failure cardiac resynchronization therapy(CRT),and to compare the PR interval prolongation in the CRT outcome of patients with heart failure and normal PR patients.The difference is to explore its clinical value.Method Patients with a normal baseline PR interval may be more likely to have a shorter right ventricular end-diastolic diameter than the prolonged PR interval,and may have a higher CRT response rate(p<0.05);binary logistic regression analysis After,QRS ? 150 ms [OR 7.449,95% CI: 1.147-48.365],RVEDD [OR 0.131,95% CI: 0.025-0.671],?LVEF [OR 1.347,95% CI: 1.106-1.640] is a CRT implant There were independent predictors of response after surgery(p<0.05).Kaplan-Meier risk function curve analysis suggested that the PR interval prolongation was higher than the re-admission of the patients with normal PR interval and the risk of reaching the composite end point.Log-rank test P value <0.05;multivariate Cox regression analysis showed CRT implantation Changes in LVEF and LBBB before surgery were independent risk factors for re-admission of heart failure after CRT(p<0.05).The PR interval was not statistically significant in the re-admission and composite endpoint multivariate Cox regression.In addition,the change in LVEF at 6 months after CRT implantation [HR 0.924,95% CI: 0.884-0.967,p=0.001],Baseline 6MWD [HR 0.995,95% CI: 0.991-0.999,p=0.007] was an independent risk factor for patients at the composite end point after CRT implantation(p<0.05).Results After binary logistic regression analysis,QRS ? 150 ms [OR 7.449,95% CI: 1.147-48.365],RVEDD [OR 0.131,95% CI: 0.025-0.671],?LVEF [OR 1.347,95% CI: 1.106-1.640] were independent predictors of response after surgery in patients with CRT implantation(p<0.05).Kaplan-Meier risk function curve analysis suggested that the PR interval prolongation was higher than the re-admission of the patients with normal PR interval and the risk of reaching the composite end point.Log-rank test P value <0.05;multivariate Cox regression analysis showed CRT implantation Changes in LVEF and LBBB before surgery were independent risk factors for re-admission of heart failure after CRT(p<0.05).The baseline PR interval was not statistically significant in the re-admission and composite endpoint multivariate Cox regression.In addition,the change in LVEF at 6 months after CRT implantation [HR 0.924,95% CI: 0.884-0.967,p=0.001],Baseline 6MWD [HR 0.995,95% CI: 0.991-0.999,p=0.007] were independent risk factors for patients at the composite end point after CRT implantation(p<0.05).Conclusions During this follow-up period,the baseline PR interval may not predict postoperative response,readmission,and death from CRT in patients with heart failure.CRT implantation has a clear benefit for patients with heart failure who have a prolonged PR interval.QRS?150ms is an independent predictor of response after CRT implantation.The more obvious right ventricular dilatation,the smaller the change of LVEF at 6 months after operation,the greater the possibility of CRT non-response;LVEF after 6 months of CRT implantation The smaller the improvement,the non-integration of LBBB before surgery was an independent risk factor for heart failure and readmission.The poor recovery of LVEF after CRT implantation and poor baseline 6MWD were independent risk factors for the composite endpoint.