Clinical,Pathological And Imaging Analysis Of Nasal Sinus Inflammatory Myofibroblastic Tumor

Objective:To investigate clinical,pathological and radiographic features of inflammatory myofibroblastic tumor(IMT)of the nasal cavity.Methods:4 cases of pathologically confirmed IMT in our hospital from April 2015 to April 2017 were retrospectively analyzed.Three dimensional CT and enhanced MRI were performed in all patients.Results:The main symptoms are local obstruction,oppression or infringement.In 4 cases,IMT was single,with 2 cases of primary maxillary sinus,1 case of nasal cavity,and 1 case of nasal septum;Pathological morphology presents diversity,consisting mainly of spindle-shaped cells distributed in bundles or whirlpools,showed inflammatory cell infiltration,immunohistochemical results showed SMA(+)in 4 cases(4/4,100%),and Desmin(-)in 4 cases(4/4,100%),ALK(-)in 3 cases(3/3,100%).CT plain tumors showed mostly uniform soft tissue densities.MR showed more enhancement of tumors,1 case of necrotic cystic changes in the maxillary sinus IMT tumors,showed a significant ring after enhancement.Conclusion:The IMT of nasal cavity and paranasal sinuses is rare and the clinical symptoms are non-specific.The diagnosis mainly depends on pathological examination and immunohistochemical staining.Preoperative CT and MRI examinations can not only provide information on the lesion locatio n,extent,and adjacent tissue invasion,but also the blood supply of the tumor and the internal components of the tissue,which will facilitate the choice of treatment options.