The Effect Of Improving The Quality Of Sleep Before Surgery On Postoperative Pain In Patients Undergoing Laparoscopic Colorectal Surgery

Objective:To observe the effect of improving the quality of sleep on the night before surgery on postoperative pain and intraoperative analgesia.Methods:Seventy patients with colorectal cancer and sleep disorders scheduled for laparoscopic radical resection of colorectal cancer under general anesthesia were enrolled in the study.The patients were randomly divided into two groups,35 patients in each group.The experimental group(S group)was given 10 mg of zolpidem tartrate one night before the operation.A blank control was applied to the control group(C group).The anesthesia induction and maintenance methods were the same in both groups.The multi-function brain monitor produced by Yifei Huatong Company was used for WLi monitoring and analgesia index monitoring.The dose of remifentanil was recorded during the operation.The dose of sufentanil at 6h(T1),12h(T2),and 24h(T3);The VAS scores at T1,T2,and T3 after surgery;the times of postoperative nausea、vomiting and pca were recorded in 24 h.RESULTS: There was a statistically significant difference between the two groups in the use of remifentanil(S group: 3.87 ± 1.30 ug /(kg.h)C group 5.68 ± 1.66 ug /(kg.h),P < 0.005)S group The use of remifentanil was lower than that of group C;the postoperative VAS pain scores in the two groups,the pain scores in the T1 and T2 time points were lower in the S group than in the C group,and there was no statistical difference in the pain scores at the T3 time point T1:(S group)VS C group(4.66±1.11 points)VS(5.80±1.18 points),P <0.05),T2:(S group VS C group(3.26±0.95 points)VS(3.94±0.97 points),P <0.05),T3 :(S group VS C group(2.37 ± 0.65 points)VS(2.57 ± 0.70 points),P > 0.05);postoperative patients with analgesic drugs,T1:(S group VS C group(13.43 ± 1.07ml)VS(15.3±3.44ml),P<0.05),T2:(S group VS C group(26.03±1.34ml)VS(29±6.24ml),P <0.05),T3:(S group VS C group(50.80± 1.96ml)VS(54.43±8.56ml),P <0.05),S group was lower than C group at three time points;24h PCA times were statistically different(S group VS C group(2.83±1.92 times)VS(6.89± 8.20 times),P <0.05)The S group was lower than the C group;there was no significant difference in the number of nausea and vomiting between T1,T2 and T3 after operation(P >0.05).Conclusion: Improving the sleep quality of patients before surgery can reduce the amount of analgesic drugs used and the degree of postoperative pain early.