| Object By analyzing the epidemic characteristics of measles from2005 to 2017and the distribution of measles antibody levels in the population of Jinshan District,and conducting a trend analysis of measles antibody levels before and after immunization,supplemented by a survey of the population‘knowledge and action'questionnaire to guide the prevention and control of measles in Jinshan District.Method Data on measles incidence from 2005 to 2017 were derived from the Chinese information system for disease control and prevention.Serum samples were collected from healthy and occupational physical examination subjects in jinshan district,and measles antibody levels were detected and the data were analyzed.The antibody levels before and after immunization were collected and analyzed.The questionnaire survey on measles knowledge and information was conducted,and the collected data were analyzed.Result A total of 236 measles cases were reported in jinshan district from 2005 to2017,with the average annual measles cases reported in each year.The incidence rates in2005,2008and2015were higher,14.52/100,000,5.58/100,000 and 3.38/100,000,respectively.Cases were reported from January to December,and the peak was from March to May.The number of measles cases among people aged 30-39 is high,which was the high incidence of measles.In the occupational distribution,workers had the highest number of cases,followed by children living in the diaspora,housework and unemployment.All the towns in jinshan district have reported measles cases,among which Zhujing town,Shihua street and Shanyang town with a large resident population rank the top three in measles incidence.The positive rate of measles antibody was 70.74%,the protective rate was 17.56%,and the geometric mean titer(GMT)was 2.52(antibody concentration was 331.13m IU/ml).The highest antibody level was found in the 65-95 age group,GMT2.65(446.68m IU/ml).The antibody level was the lowest in the 15-24 age group GMT2.46(288.40m IU/ml),and the difference was statistically significant among all age groups(F=6.64,P<0.05).The age group 15-24 had the lowest protective rate(9.60%).The 65-95 age group was the highest(25.62%),with statistically significant differences among all age groups(?~2=44.53,P<0.05),and the antibody protection rate increased with age(?~2=42.96,P<0.05).The positive rate of measles antibody in professional medical was 87.06%,the protective rate was 28.63%,and the GMT was 2.69(489.78m IU/ml).The highest antibody level was found in the 55-64 age group(2.81 GMT).The 15-24 age group had the lowest antibody level GMT2.56(363.08m IU/ml),with statistically significant differences among all age groups(F=7.55,P<0.05).The age group 15-24 had the lowest protective rate(14.46%).The 55-64 age group was the highest at 45.45%,with statistically significant differences among all age groups(?~2=19.40,P<0.05),and showed an increasing trend with the increase of age(?~2=5.49,P<0.05).Permanent population pre-immunization antibody levels were<200,200-,400-groups,antibody levels rose after vaccination,and all<200 groups turned to positive,GMT increased by 612.36m IU/ml,87.50%of 200-groups reached protection level,GMT Increased 826.90m IU/ml,57.14%of the 400-group reached the protection rate level,and GMT increased by 862.51m IU/ml.The total pass rate of measles related knowledge of the resident population in jinshan district is 54.79%,and the knowledge rate of each knowledge point is between21.72%-90.75%.The pass rate of measles related knowledge of the population of primary school and below,middle school,high school/technical secondary school,college,undergraduate and above is 23.64%,38.05%,47.24%,43.46%,52.34%.The population with household registration and the population with foreign household registration are42.75%and 42.16%,respectively.It was 37.82%for men and 44.55%for women.There were statistically significant differences in the knowledge rate of measles among people with different educational levels(?~2=20.94,P<0.05).Among the respondents,85.63%(1037/1211)were willing to receive measles vaccine.Multivariate logistic analysis showed that low educational background and lack of measles knowledge were risk factors for vaccination intention(P<0.05).Conclusion From 2005 to 2017,the incidence of measles in Jinshan District showed a low level.In 2018,monitoring of measles antibody levels in healthy and occupational populations showed that the antibody level was the lowest in the 15-24 age group,and the immune barrier has not yet formed in this age group.MV vaccination is the most cost-effective measure to increase the antibody level of the population.It is also necessary to carry out targeted publicity on measles knowledge and policies to improve the health awareness of residents in Jinshan District,thereby increasing the MV vaccination rate of residents.Jinshan District requires joint prevention and control by all parties.Health promotion and measles vaccination should be carried out for key populations to reduce the number of immune failures and“immunity gaps”and strengthen the population's immune barrier. |
PDF Full Text Request