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99mTc-DAPA Renal Dynamic Imaging Has Unique Value In Stent Implantation Of Atherosclerotic Renal Artery Stenosis

Posted on:2021-05-06Degree:MasterType:Thesis
Country:ChinaCandidate:L DuanFull Text:PDF
GTID:2404330602962723Subject:Imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Objective:To evaluate the predictive value of 99mTc-DAPA renal dynamic imaging for stent implantation in atherosclerotic renal artery stenosis.Methods:For 45 patients with atherosclerotic renal artery stenosis,a total of 54 patients with renal artery stenosis underwent renal artery stent implantation(percutaneous transluminal renal angioplasty and stent,PTRAS),99mTc-DAPA renal dynamic imaging was performed within 2 weeks before surgery and 6 months after operation respectively,the glomerular filtration rate of the affected side was measured by Gates method(glomerular filtration rate,GFR),creatinine,blood pressure.According to the results of preoperative GFR determination of renal function can be divided into GFR level I(GFR≥30 ml/min),GFR level II(15ml/min≤GFR<30 ml/min)and GFR levelⅢ(GFR<15 ml/min).GFR,renal perfusion and function of the affected kidney before and after operation were analyzed.Preoperative and postoperative changes in blood pressure,types and doses of antihypertensive medicines,and serum creatinine(SCr)changes.Results:postoperative GFR was evidently improve,especially GFRI,GFRⅡ,increased renal perfusion,period is higher than the GFRⅢlevel,statistically significant difference(P<0.05).GFRI、Ⅱpatients postoperative patients with high blood pressure,the higher than that of GFRⅢlevel,no statistically significant difference(P>0.05).Postoperative systolic blood pressure decreased from(165±18)mmHg to(138±12)mmHg,and diastolic blood pressure decreased from(100±12)mmHg to(88±8)mmHg.The dose of antihypertensive medicines was lower than that before operation.The difference was statistically significant(P<0.05);There was no significant difference in SCr before and after operation(P>0.05).Unilateral treatment was better than bilateral treatment,and the difference was statistically significant(P<0.05).Conclusion:99mTc-DAPA dynamic renal imaging can be used to evaluate the efficacy of stent implantation for atherosclerotic renal artery stenosis.
Keywords/Search Tags:Atherosclerotic renal artery stenosis, Radionuclide imaging, Balloon dilation and stent implantation
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