The Clinical Observation Of TaiChi Tuina In The Treatment Of Chronic Insomnia And Its Effect On Serum CRP And IL-6

Objective To explore the clinical efficacy and mechanism of TaiChi Tuina in the treatment of chronic insomnia by observing the effects of TaiChi Tuina on sleep quality and serum inflammatory factors CRP and IL-6,so as to provide new ideas and methods for clinical treatment and research of chronic insomnia.Method Sixty patients with chronic insomnia meeting the inclusion criteria were randomly divided into experimental group(n = 30)and control group(n = 30)using a random number table in a 1: 1 ratio.The experimental group was treated with head and face manipulation of TaiChi Tuina,one treatment per day and 5 times a week.the control group was treated with auricular acupuncture,and the needles were changed every 3 days and twice a week.The patients in the two groups were treated for a total of 4weeks.The changes of sleep diary,Pittsburgh sleep quality index(PSQI)score,insomnia severity index(ISI)score,and serum inflammatory factors CRP and IL-6 were compared between the two groups before and after treatment.Result 1.Analysis of the characteristics of included cases: At the end of this study,56 patients were included,including 19 males(33.9%)and 37 females(66.1%).Before treatment,the two groups are comparable in sex,age,course of disease,education level and professional status(p >0.05).The general data were basically the same and comparable.2.Comparison of sleep diary factors before and after treatment:Before treatment,the factors of sleep diary in two groups are comparable(p>0.05).After treatment,the factors of sleep diary in both groups improved compared with before treatment(p < 0.05).The improvement of the experimental group was better than the control group in sleep time,number of night awakenings and sleep efficiency(p<0.05).The experimental group and the control group showed similar improvement in sleep latency(p>0.05).3.Comparison of Pittsburgh Sleep quality Index(PSQI)score and insomnia severity index(ISI)score before and after treatment:Before treatment,the scores of PSQI and the scores of ISI in two groups are comparable(p>0.05).After treatment,the score of PSQI and the scores of ISI in both group s improved compared with before treatment(p<0.05),and the improvement of the experimental group was better than that of the control group(p<0.05).4.Comparison of serum levels of inflammatory factors CRP and IL-6 before and after treatment:Before treatment,the serum CRP and IL-6 in two groups are comparable(p>0.05).After treatment,the serum CRP and IL-6 in both groups improved compared with before treatment(p < 0.05),and the improvement of the experimental group was better than that of the control group(p<0.05).Conclusion 1.TaiChi Tuina is effective in the treatment of chronic insomnia.TaiChi Tuina is superior to auricular acupuncture in improving sleep time,number of night awakenings,sleep efficiency,PSQI score and ISI score.TaiChi Tuina has similar effect with auricular acupuncture in improving sleep latency.2.TaiChi Tuina can reduce the levels of inflammatory factors CRP and IL-6 in patients with chronic insomnia,and the effect is better than that of auricular acupuncture.Regulating the level of inflammatory factors may be one of the mechanisms of TaiChi Tuina to improve sleep quality.3.There are no obvious adverse reactions and events during the treatment of head and face manipulation of TaiChi Tuina,so it is safe and effective to treat patients with chronic insomnia with TaiChi Tuina.