Study On Distribution Char Acteristics Of TCM Syndromes In Elderly Patients With Carotid Atherosclerosis

Purpose: This topic through detailed clinical data collection,study aged Carotid artery atherosclerosis(Carotid atherosclerotic diseases,CAD)in patients with TCM syndrome type distribution characteristics,provide reference for the standardization of the syndrome differentiation and treatment in patients with CAD.Methods: Collected in January 2019-January 2020 in yunnan province,Chinese medicine hospital inpatient,carotid artery color doppler ultrasound examination,diagnosis of carotid artery atherosclerosis and 226 patients older than 60 years of relevant data,to carry on the type of traditional Chinese medicine,as qi deficiency and blood stasis syndrome,qi and Yin deficiency syndrome,phlegm and blood stasis and each type of syndrome,qi and blood stasis,and other five card type,after statistical analysis to discuss the distribution characteristics of TCM syndrome types.Results: 226 cases of aged patients with carotid atherosclerosis were collected.(1)distribution frequency of TCM syndromes: qi deficiency and blood stasis syndrome(27.9%),> qi and Yin deficiency syndrome(25.7%),> mutual phlegm and blood stasis syndrome(21.2%),> qi stagnation and blood stasis syndrome(15.9%),> other syndromes(9.3%).(2)correlation factors: in the analysis of gender,tobacco and alcohol history,history of hypertension,history of diabetes,history of stroke,plaque location,plaque hardness,plasma Fibrinogen FIB,Homocysteyne Hcy and other factors,there was no significant correlation between different syndromes.(3)age characteristics: patients with qi deficiency and blood stasis syndrome and qi and Yin deficiency syndrome are older,mainly between 76 and 85 years old;The syndromes of phlegm and blood stasis and qi stagnation are relatively young,mainly between 65 and 75 years old.(4)distribution characteristics of biochemical indexes: Total cholesterol TC,Triglycerides TG and Low density lipoprotein ldl-c presented different distributions ondifferent TCM syndromes.Mean TG value: syndrome of qi stagnation and blood stasis < deficiency of qi and Yin < other syndromes < deficiency of qi and blood stasis < mutual settlement of phlegm and blood stasis;Ldl-c mean: qi and Yin deficiency syndrome < other syndromes < mutual phlegm and blood stasis syndrome < qi deficiency and blood stasis syndrome < qi stagnation and blood stasis syndrome;(3)mean value of TC: qi deficiency and blood stasis syndrome < qi and Yin deficiency syndrome < qi stagnation and blood stasis syndrome < other syndromes < mutual settlement of phlegm and blood stasis syndrome.(5)characteristics of intima-media thickness IMT in the carotid artery: the mean value of intima-media thickness in patients with five syndromes was greater than 1.1mm,and the syndrome of qi stagnation and blood stasis < phlegm and blood stasis interaction < qi and Yin deficiency < qi deficiency and blood stasis.IMT values of different syndromes were statistically significant.(6)plaque characteristics: the proportion of hard plaque was 75.7%,the proportion of soft plaque was 8.8%,and the proportion of mixed plaque was 15.5%.There were 83 cases(33.3%)with plaques in the common carotid artery.The incidence of internal carotid artery in 56 patients was24.8%.There were 87 cases at the intersection of carotid artery,accounting for 38.5% of the total cases.Conclusion:1.The distribution of TCM syndrome differentiation in CAD patients is mainly composed of four syndromes: qi deficiency and blood stasis,qi and Yin deficiency,phlegm and blood stasis,and qi stagnation and blood stasis.Among them,qi deficiency and blood stasis are the most common syndromes,followed by qi and Yin deficiency.2.Different syndrome types have differences in age,IMT value,TC,TG and ldl-c.There were differences in the distribution of syndromes in patients of different age groups: the syndromes of phlegm and blood stasis were more common in patients aged 60-75 years.From 76 to 90 years old,qi deficiency and blood stasis were more common.90 years old with qi Yin deficiency syndrome is more common.There was a statistical difference between the distribution of IMT and syndrome types,among which the syndrome of qi deficiency and blood stasis was the most common and the highest.The values of TC and TG were the highest in the syndrome of phlegm and blood stasis,and the values of ldl-c were the highest in the syndrome of qi stagnation and blood stasis.3.There was no correlation between the distribution of TCM syndromes in CAD patients and the patient’s gender,comorbidity,tobacco and alcohol history,plaque type,and homocysteine level.