To Investigate The Effect Of Brain Oxygen Saturation Monitoring On Cognitive After Abdominal Endoscopic Surgery In Elderly Patients

Objective:To explore the effect of different cerebral oxygen saturation values on postoperative cognitive function in elderly patients undergoing laparoscopic surgery.Methods:According to the inclusion exclusion criteria,90 elderly patients who underwent elective laparoscopic surgery in our hospital from October 2018 to June 2019 were randomly divided into three groups:experimental group（group A cerebral oxygen saturation（regional cerebral oxygen saturation）rScO₂ 55%to 65%,group B rScO₂ 66%to 75%）and control group（group C:cerebral oxygen saturation monitoring）,neuron-specific enolase was performed on patients before surgery,1hour during surgery,and after surgery（neuron-specific enolase NSE）,S100βprotein content determination,and the 1d preoperative,1d postoperative,7d postoperative simple mental status examination scale（MMSE）,Montreal Cognitive Assessment Scale（Mo CA）,analysis of three groups Occurrence of neurocognitive disorder（PND）in patients during perioperative period.Results:PND occurred in 12 cases in group C,5 cases in group A,and 4 cases in group B.The intraoperative and postoperative NSE and S100βproteins of groups A and B were lower than that of group C,and the difference was statistically significant（P<0.05）;the intraoperative and postoperative NSE and S100βproteins of group A were slightly higher than that of group B,and there was no difference Statistical significance（P>0.05）.The MMSE and Mo CA of the two groups A and B were higher than that of the C group at 1d and 7d after operation,and the difference was statistically significant（P<0.05）;the MMSE and Mo CA of the A group at 1d and7d after operation were slightly lower than those of the B group The difference was not statistically significant（P>0.05）.Compared with group C,the postoperative mechanical ventilation time and recovery room observation time in groups A and B were shortened,but the difference was not statistically significant（P>0.05）.Conclusion:The reduction of rScO2 in elderly patients during operation may cause PND,and maintaining rScO2 within a certain range during operation may reduce the occurrence of PND.There is a correlation between the decrease of rScO2and the occurrence of PND during operation.Monitoring rScO2 has important clinical significance。...