Impact Of Computed Tomography Attenuation Of Pericoronary Adipose Tissue On Coronary Stenosis And In-Hospital Adverse Event

Objective: To investigate the correlation between the computed tomography(CT)attenuation index of peripheral coronary artery fat(PCAT)and non-calcified lesions in the coronary arteries and in-hospital adverse events,and to explore the cut-off of the CT attenuation index of the PCAT to evaluate coronary stenosis.Methods: Patients who underwent coronary angiography within 1 month after undergoing coronary CT(CTA)at Shengjing Hospital of China Medical University from January 2018 to December 2018 were analyzed.According to the results of coronary angiography,patients were divided into high stenosis group and non-high stenosis group.Logistic regression was used to analyze the relationship between clinical characteristics and adverse events in the two groups.Results: Logistic regression analysis showed that the CT attenuation index of PCAT in smoking,diabetes,hypertension,low-density lipoprotein and corresponding lesions was a risk factor for non-calcified plaque height stenosis(P <0.05),and the CT attenuation index of PCAT was the mere risk factor for in-hospital adverse events(OR 1.04,95% confidence interval: 1.01 1.07).For highly stenotic lesions,according to the receiver operating characteristic curve(ROC),the CT attenuation index of PCAT =-82.13 HU corresponds to the maximum Judden index.At this time,the sensitivity of the CT attenuation index of PCAT is 79.75%,and the specificity is 76.67%.Conclusion: The CT attenuation index of PCAT is directly proportional to the degree of non-severe calcified stenosis,whose optimal cutoff to diagnose high stenosis is-82.13 HU.It is also the independent risk factors of in-hospital adverse events.