| Objective:In chengde area hospitalized children with mycoplasma pneumoniae pneumonia(MPP)during the analysis of the clinical data and recovered after 1year follow-up,designed to children with statistical MPP recovery related disease,the incidence of ahr,look for these related disease relationship with the clinical features of the patients and its related risk factors,for clinical doctors to MPP patients recovery in treatment of airway hyperresponsiveness related disease plays a guiding role,and the condition for the recovery of pneumonia changes do early detection,early intervention,reduce the complications caused by the adverse consequences.Methods:A total of 287 children diagnosed as MPP in chengde central hospital from September 2018 to February 2019 were selected as subjects.Clinical data were collected during hospitalization: general situation(name,gender,place of residence,nationality,contact information,etc.),clinical characteristics,laboratory examination indicators,and treatment plan,and were followed up for 1 year,mainly by outpatient or telephone follow-up.Fill in the follow-up record form,and make a detailed record of the follow-up,such as diagnosis,relevant examination results,treatment and disease outcome.Statistics were made on the occurrence of airway hyperreactivity related diseases within 1 year after her recovery from hospital,including chronic cough,infant wheezing,asthmatic bronchitis,asthmatic bronchopneumonia,asthma,etc.Will be the research object,according to whether children during follow-up after discharge in airway hyperresponsiveness disease into two groups,respectively is the airway hyperresponsiveness disease group(asgroup)and airway hyperresponsiveness disease group(set as control group),compared two groups of children with relevant clinical data and its relationship with disease recovery airway hyperresponsiveness,looking for MPP recovery in airway hyperresponsiveness related disease risk factors.Results:1.In the observation group,there were 63 cases,accounting for21.95% of the total cases.The control group included 224 cases,accounting for 78.05% of the total cases.2.In the observation group,there were 34 cases of chronic cough,accounting for 11.85% of the total cases.Asthmatic diseases accounted for 29 cases,accounting for 10.10% of the total cases.There were 32 cases of chronic cough with post-infection cough(incidence: 11.15%)and 2 cases of cough-variant asthma(incidence: 0.70%).Asthma was found in 6 cases of asthmatic diseases,with an incidence of 2.09%.The incidence of asthmatic bronchitis was 5.92% in 17 cases.There were 5 cases of asthmatic bronchopneumonia,with an incidence of 1.74%.The incidence of wheezing in1 case was 0.35%.3.There were 10 children with atopic constitution in the observation group,accounting for 15.87%,and 224 children in the control group,including 12 children with atopic constitution,accounting for 5.36%.The rate of children with atopic constitution in the airway hyperreactive disease group was significantly higher than that in the control group,with a statistically significant difference(X2=7.682,P < 0.05).4.In the observation group,there were 15 cases of wheeze in the acute stage of pneumonia,accounting for 23.81%;in the control group,there were 26 cases of wheeze in the acute stage of pneumonia,accounting for13.61%.The incidence of wheeze in the acute stage of pneumonia in the observation group was higher than that in the control group,with a statistically significant difference(X2=5.979,P < 0.05).5.In the observation group,8 children developed pleural effusion in the acute stage of pneumonia,accounting for 12.70%;in the control group,12 children developed pleural effusion in the acute stage of pneumonia,accounting for 5.36%;in the observation group,the proportion of patients with pleural effusion was significantly higher than that of the control group,with a statistically significant difference(X2=4.088,P < 0.05).6.Compared with the two groups,the average length of hospitalization was(7.95±2.81)d in the observation group and(6.26±2.99)d in the control group.The length of hospitalization in the observation group was longer than that in the control group,and the difference between the two groups was statistically significant(Z =-3.33,P < 0.05).7.The blood sedimentation rate in the observation group and the control group was(45.71±25.11)mm/h and(34.00±21.10)mm/h,respectively.The blood sedimentation rate in the observation group was faster than that in the control group,and the difference was statistically significant(Z =-2.996,P< 0.05).8.The hormone application rate was 19.05% in 12 cases in the observation group,and 32.14% in 72 cases in the control group.The hormone application rate in the control group was significantly higher than that in the observation group,and the difference between the two groups was statistically significant(X2=4.073,P < 0.05).9.By single factor analysis of the difference was statistically significant indicators as independent variable,whether disease as the dependent variable,airway hyperresponsiveness multiariable logistic regression analysis found that atopic physical(OR = 3.54,95% CI = 1.383 ～9.100),pneumonia,acute period of onset of breathing(OR = 2.246,95% CI =1.079 ～ 4.675)is children with MPP airway hyperresponsiveness in disease recovery related disease risk factors.Cinclusion:1.The incidence of airway hyperreactive diseases in convalescent children with mycoplasma pneumoniae in chengde area was about 21.95%,and the airway hyperreactive diseases found in follow-up included chroniccough(post-infection cough,cough variant asthma),infant wheezing,asthmatic bronchitis,asthmatic bronchopneumonia,and asthma.2.Children with atopic constitution,acute pneumonic wheeza,pleural effusion and accelerated blood sedimentation are prone to hyperreactive diseases in convalescence.3.The use of hormones can reduce the incidence of airway hyperreactive disease in convalescence of children with mycoplasma pneumoniae pneumonia.4.Atopic constitution and acute pneumonic wheeaning are independent risk factors for airway hyperresponsiveness in children with mycoplasma pneumoniae in convalescence. |
PDF Full Text Request