Predictive Value Of Severe Calcification Of Coronary Artery For Coronary Stenosis

Objectives:To analyze the degree of vascular stenosis at the site of severe calcification of coronary artery and the relationship between calcium score of severe calcification and the degree of vascular stenosis at the same site,then to study the significance of severe calcification of coronary artery in the diagnosis and severity assessment for coronary heart disease(CHD).Methods:Data was retrospectively collected between January 2016 and May 2019.We enrolled 100 patients with severe calcification(the calcification lesion was defined as severe calcification in this study because the degree of vessel stenosis could not be evaluated visually by c CTA)who underwent coronary computed tomography angiography(c CTA)and coronary angiography(CAG)within one month.The site of severe calcification was identified by c CTA as the standard,the calcium score of severe calcification and the total calcium score of the patient were calculated;the degree of vascular stenosis at the same site was evaluated by CAG as the standard,and the Gensini score was calculated.Observed the most common vascular location and the distribution of vascular stenosis in severe calcification.The statistical analysis was used to analyze the relationship between the calcium score of severe calcification and vascular stenosis,total calcium score and the calcium score of severe calcification,Gensini score and its influence factors.Results:1 In the 100 patients,there were 64 males;the age was 47 to 81 years and the mean age was 62.91±7.18 years;60 patients with hypertension;23 patients with diabetes;46 patients with dyslipidemia;6 patients with family history;52 patients are smokers;17 patients with obesity,body mass index(BMI)was 18.34 to 41.02 kg/m2.2 The most common vessels with severe calcification were the left anterior descending artery(LAD)and the right coronary artery(RCA),and the proximal part of the vessel was the most common.In terms of 189 severe calcification segments,the highest proportion of mild stenosis(stenosis<50%)was 60.85%,CHD(stenosis ≥ 50%)was only 39.15%,and requiring percutaneous coronary intervention(PCI)(stenosis>75%)accounted for the least 16.93%.3 The calcium score of severe calcification was 372.79±294.90,which was positively correlated with vascular stenosis(r:0.15,P<0.05).4 Total calcium score of patients was positively correlated with the calcium score of severe calcification(r:0.889,P<0.05),Gensini score(r:0.214,P<0.05).5 For patients with severe calcification,age is an independent influence factor for total calcium score.Conclusions:Severe calcification of coronary arteries does not mean that coronary stenosis is severe.For patients with severe calcification of coronary artery shown by c CTA,the proportion of CHD was not high,fewer patients had lesions that were narrow enough to require PCI.Severe calcification of coronary arteries has limited significance in the diagnosis and severity assessment for CHD.