| Objective:Inheriting the experience of famous old Chinese medicine,on the basis of disease differentiation and syndrome differentiation of western medicine,observe the effect of Professor Yan Guizhen’s self-prepared Pingchuan Decoction combined with salmeterol ticasone powder inhalation on elderly patients with chronic bronchial asthma with chronic deficiency of yang and phlegm To evaluate the clinical efficacy and provide a certain reference for the treatment of chronic bronchial asthma in the elderly with integrated Chinese and Western medicine.Methods:Seventy-two elderly patients with chronic bronchial asthma with chronic yang deficiency and phlegm and blood stasis syndrome were selected and randomly divided into a control group and an observation group,with 36 cases in each group.The control group was inhaled with salmeterol ticasone powder inhalation.The observation group was treated with the self-made Pingchuan decoction on the basis of the control group for 4 weeks,and then followed up for 4 weeks.Observe the changes of TCM syndrome scores,lung function(FEV1,PEF),serum IgE,peripheral blood EOS and other indicators of the two groups of patients before and after treatment,and observe the changes of ACT score and number of acute asthma attacks before,after and after 4 weeks of treatment.Results:1.Comparison of ACT scores between the two groups: after treatment,the ACT scores of both groups were higher than before treatment(P <0.01);after treatment and after 4 weeks of follow-up in both groups,the ACT scores of the observation group were significantly improved(P <0.01).2.Comparison of lung function between the two groups: after treatment,FEV1 and PEF were higher than before treatment(P <0.01);after treatment,the observation group improved FEV1,PEF and the control group had no significant difference(P >0.05).3.Comparison of TCM syndrome scores between the two groups: The total score of TCM syndromes after treatment in both groups decreased compared with that before treatment(P <0.01);the total score of TCM syndromes in the observation group after treatment was more significantly improved than that of the control group(P <0.01)After treatment,the observation group was better than the control group in improving symptoms such as wheezing,chills,cold limbs,sore waist and knees,fatigue,spontaneous sweating and other symptoms(P <0.05).4.Comparison of serum IgE between the two groups: after treatment,the serum IgE of both groups decreased compared with before treatment(P <0.01);after treatment,the observation group improved serum IgE better than the control group(P <0.05).5.Comparison of peripheral blood EOS between the two groups: after treatment,the peripheral blood EOS decreased compared with before treatment(P <0.01);after treatment,the observation group improved peripheral blood EOS and the control group had no significant difference(P >0.05).6.Comparison of the number of acute asthma attacks between the two groups: the control group had no significant difference in the number of acute asthma attacks between 4 weeks of treatment and 4 weeks of follow-up(P >0.05),and the number of acute attacks of asthma inthe observation group after 4 weeks of follow-up decreased compared with 4 weeks of treatment(P <0.05);There was no significant difference in the number of acute attacks of asthma between the observation group and the control group after 4 weeks of treatment(P >0.05),and the number of acute attacks of asthma in the observation group after 4 weeks of follow-up was less than that of the control group(P <0.05).7.Comparison of clinical efficacy between the two groups: the total effective rate of the control group was 85.29%,the total effective rate of the observation group was 94.29%,and the efficacy of the observation group was better than that of the control group(P <0.05).Conclusion:1.Self-made Pingchuan Decoction combined with salmeterol ticasone powder inhalation for the treatment of elderly patients with chronic bronchial asthma with chronic deficiency of yang and phlegm and blood stasis syndrome,the total effective rate is better than that of salmeterol ticasone powder inhalation alone The efficacy of medication can improve the patient’s ACT score,improve the patient’s clinical symptoms,reduce the number of acute attacks,and reduce serum IgE levels.2.The self-made Pingchuan decoction combined with salmeterol ticasone powder inhalation in the treatment of elderly patients with chronic bronchial asthma with chronic yang deficiency and phlegm and blood stasis syndrome has a long-term effect.The ACT score is relatively stable during the follow-up period,and the number of acute attacks is reduced.Can reduce the risk of future asthma instability and acute exacerbation. |
PDF Full Text Request