Meta-analysis Of Surgical Resection And Transcatheter Arterial Chemoembolization In The Treatment Of Hepatocellular Carcinoma Complicated With Portal Vein Tumor Thrombus

Objective:To explore the clinical effect of surgical resection and transcatheter arterial chemoembolization(TACE)in the treatment of resectable hepatocellular carcinoma with portal vein tumor thrombus with Child A-B grade liver function.Methods:The controlled clinical trials of surgical resection and TACE in the treatment of hepatocellular carcinoma with portal vein cancer thrombus in CNKI,Wanfang database,PubMed and The Web of Science from July 1,2010 to July 1,2019,and the RevMan 5.3software was used for meta-analysis.Results:A total of 1129 patients were included in 4 literatures,including TACE group(n =702)and surgical resection group(n = 427).The results of Meta analysis showed that the1-,2-and 3-year survival rates in the surgical resection group were significantly higher than those in the TACE group,but there was no significant difference in 5-year survival rate between the two groups.Conclusion:Patients with resectable hepatocellular carcinoma with portal vein tumor thrombuswithout distant metastasis with Child A Mel B liver function were treated with surgical resection,and the survival rate was higher than that of TACE treatment to some extent,so it was suitable to be carried out in large liver surgery centers with conditions.