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Epidemiological Characteristics And Prognostic Factors Of Inpatients With Inhalation Injury In Burn Center In Jiangxi

Posted on:2021-05-24Degree:MasterType:Thesis
Country:ChinaCandidate:L ZhangFull Text:PDF
GTID:2404330629486434Subject:Surgery
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Objective:The clinical epidemiological characteristics of hospitalized patients from January2014 to December 2018 were retrospectively analyzed with inhalation injury in jiangxi’s burn center,to provide reference for the development of corresponding prevention and treatment measures.Method:1.430 patients with inhalation injury admitted were collected from January 2014to December 2018.Among them,50 patients with age less than or equal to 18 years old were in the children group,298 patients with age less than or equal to 65 years old were in the middle-aged and young group,and 82 patients with age greater than 65years old were in the elderly group.2.Statistical analysis was made on the demographic data of patients,Characteristics of injuries of hospitalized patients,the status of hospitalized treatment and the treatment results.Data were processed with nonparametric Kruskal—Wallis、chi—square test and Fisher’s Exact Test.Spearman method was used to analyze the correlation between variables,and Logistic regression analysis was performed for the risk factors of poor outcomes.Results:1.Demographic data The three groups of patients were mainly male,with no statistical difference in distribution(?~2=4.708,P=0.095).There was no significant statistical difference in the seasonal distribution among the three groups,which were mainly in summer(?2=7.135,P=0.309).The three groups of patients lived mainly in rural areas,with no statistical difference in distribution(?~2=2.961,P=0.230).There was a significant statistical difference in the distribution of educational level among the three groups,with the latter dominated by secondary education and the latter dominated by primary education(?~2=32.070,P<0.001).2.Admission status There was no significant statistical difference in the distribution of burn causes among the three groups,and the three groups were mainly flame burns(P=0.251).Compared with the children group and the young and middle-aged group,the elderly group had a higher risk of delayed resuscitation,but there was no significant statistical difference in the overall distribution among the three groups(?2=3.060,P=0.217).Most of the patients with inhalation injury were admitted within 6 hours(?2=1.042,P=0.903).The incidence of third degree burns is high in patients with inhalation injury(the children group78.0%,the middle-aged and young group 82.9%,elderly group78%).There were significant differences in total burn area(TBSA)and third-degree burn area among the three groups,with the younger and middle-aged groups having larger TBSA and third-degree burn areas than the younger and older groups(H=11.334、15.480,P=0.003、P<0.001).3.Tracheotomy and operation Tracheostomy in children group,middle-aged and young group and elderly group was 40.0%,48.3%and 37.8%,respectively,with no significant difference in distribution(?~2=3.523,P=0.172).The proportion of tracheotomy in three groups within 6 hours was 45.0%,32.6%and 35.5%,respectively,there was no significant difference in the distribution.The proportion of the elderly group without surgery was 63.1%,significantly higher than the other two groups(28.0%in the children group and 32.2%in the young and middle-aged group)(?~2=28.914,P<0.001).The rate of complications in the treatment of the elderly group was higher than that of the other two groups(the elderly group 64.3%、the young and middle-aged group 59.1%、the children group 54.0%),there was no significant difference in the distribution(?2=1.549,P=0.461).4.Treatment outcome The proportion of adverse outcomes in the pediatric group,the middle-aged and young group and the elderly group was 10.0%,27.2%and 53.7%,respectively,and the risk of adverse outcomes in the three groups was statistically different(?~2=34.931,P<0.001).The hospitalization days of children group,middle-aged and young group and old group were 34.86±33.75,31.16±27.75 and 14.77±15.87,respectively,there were significant statistical differences(H=32.973,P<0.001).The treatment cost was 18.47±27.08,25.99±27.26 and9.91±14.07 in the children group,the young and middle-aged group and the elderly group,respectively,showing significant statistical differences(H=33.302,P<0.001).5.Prognostic factor analysis There are 130 patients with poor outcomes.The influencing factors of adverse outcomes were TBSA,age,shock,and surgery,among which surgery was the protective factor of adverse outcomes,while the other were risk factors.Conclusion:1.Among the hospitalized patients with inhalation injury,the proportion of young and middle-aged patients was the highest.They are prone to burn in summer.flame was the main pathogenic factor.2.TBSA was the most important factors for adverse outcomes in patients with inhalation injury,then were age and shock.Timely surgical treatment of the wound can improve the patient’s prognosis.
Keywords/Search Tags:inhalation injury, epidemiological investigation, prognosis, Logistic regression
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