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A Study On The Clinical Efficacy Of Modified Xiao-Xu-Ming-Tang On Ureteral Stent-Related Complications After Urolithiasis

Posted on:2020-04-28Degree:MasterType:Thesis
Country:ChinaCandidate:D Y ShengFull Text:PDF
GTID:2404330647456238Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Objective:To Observe Clinical efficacy of modified Xiao-Xu-MingTang in the treatment of complications like Pain and hematuria in patients with ureteral stents indwelling after urinary calculi,and evaluate it through statistical analysis of objective indicators like Pain points and some related scales,Then to explore the clinical value and security of modified Xiao-Xu-Ming-Tang After ureteral stenting.Method: 106 cases of patients with urinary calculus and meeting the standard were included in our study(all patients were from Yueyang Hospital of Integrative Chinese & Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine).All patients were divided into treatment group and control group by random number method.The patient underwent laser lithotripsy after excluding surgical contraindications.After the operation,the two groups received conventional symptomatic treatment.the treatment group received modified Xiao-Xu-Ming-Tang after 24 h,and continued to take Chinese medicine for 1 month.During the intervention,we will observe and record variety of symptoms of patients,like fever,blood in urine situation and LUST.In the meantime,TCM syndrome integral,postoperative pain score,OABSS score,IPSS score and QQL grading index will be counted;Some rare complications wii be cunted,such as ureter mucosa avulsion,Serious bleeding and urinary tract infection,sepsis,ureteral stents slippage and retraction,etc.Finally,analyze the data differences between the two groups with SPSS.Results: 106 patients were included in this study,including 55 in the treatment group and 51 in the control group.There was no significant difference in gender between the two groups by chi-square test(p=0.52);T test showed no significant difference in age between the two groups(p=1.023),and no significant difference in stone size between the two groups(p=0.53);There was no significant difference in stone site by chi-square test(p=0.46);there was no significant difference in pain scores and TCM syndrome scores between the two groups on the first day after surgery(p values were 0.98 and 1.191,respectively).The results showed that the two groups were comparable After treatment,TCM syndrome scores of patients in both groups decreased on the 5th and 30 th day after the operation,and the decline was more significant in the treatment group than in the control group(p<0.05).The pain scores of patients in both groups gradually decreased,and on the 30 th day after the operation,there was significant difference in pain improvement between the two groups,but no difference on the 5th day.By non-parametric test,there was no statistically significant difference in postoperative duration of hematuria and postoperative gross hematuria frequency between the two groups(p=0.49).There were statistically significant differences in OABSSscore(p=0.009)and QQL score(0.042)between the two groups by nonparametric test,but not in IPSS(p=0.075).There were no patients with liver and kidney dysfunction or other serious complications in the two groups.Conclusion: Modified Xiao-Xu-Ming-Tang has a goodcurative effect on patients with urolithiasis after operation,wich can significantly reduce patients’ TCM syndrome score and improve clinical symptoms.Although modified Xiao-Xu-Ming-Tang has no obvious advantage in the short-term pain after calculi operation,it has certain curative effect on catheter-related pain and LUTS.During the course of this study,no serious complications such as serious ureter injury,stent slippage,liver and kidney function injury occurred in the patients who took the medicine.It can be seen that the clinical efficacy of modified Xiao-Xu-Ming-Tang in the treatment of postoperative catheterrelated complications of calculi is definite and safe.
Keywords/Search Tags:Ureteral stent, complication, Xiao-Xu-Ming-Tang
PDF Full Text Request
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