| Purpose: This study summarized the epidemiological data of gastric ulcer,duodenal ulcer and compound ulcer,the causes of ulcer,Helicobacter pylori test results,symptoms and signs,TCM Syndrome Types and treatment methods.To explore the epidemiological rule of patients,the causes of common diseases,and the distribution of Hp infection in different gender,age groups,Western Medicine Classification and TCM syndrome types.The symptoms and signs were analyzed by cluster analysis,and the results were compared with the diagnostic criteria.This article also statistics the TCM syndrome type and the different traditional Chinese medicine.All the work provides reference for the treatment of clinical peptic ulcer with Chinese medicine.Material and method: The subjects were peptic ulcers hospitalized at the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2015 to March 2017.In this paper,a retrospective study was used to induce 165 cases of clinical cases conforming to the inclusion and exclusion criteria.The collected results are entered into the software SPSS19.0.Age,season,course of disease,smoking,drinking,and causes of disease were checked with chi square test.If the result is P<0.05,the difference is significant;the result is P<0.01,and the difference is very significant.The frequency of symptoms and signs and the frequency of traditional Chinese medicine were recorded at the same time.And using K-means clustering method(K-mean Cluster Analysis)analysis of the four diagnostic information of TCM.Results: 1 General situationA total of 165 cases of PU were reported in this study,including 73 patients with GU,75 cases of DU and 17 cases of CU.GU:DU:CU=4.29:4.41:1,DU:GU=1.03:1.There were 108 male and 57 female,male / female =1.89:1,GU:male / female =1.70:1,DU:male / female =2:1,CU:male / female =2.4:1.The average age of GU patients in this study is 55.32 + 9.94 years,the average age of DU patients is 51.08 + 11.54 years,and the average age of CU patients is 54.06 + 11.65 years old.The age of female patients is 55.23 + 9 years,and the average age of male patients is 52.22 + 11.82 years.The average age of DU patients is about 4 years younger than that of GU patients.The number of patients at the age of 51-60 is the most.At the age of 40-60,the number of PU diseases increased with age.Before the age of 50,the number of patients with DU was significantly more than that of GU patients.The 51-60 year old group is basically equal.The number of GU patients in the 61-70 year old group was higher than that of the DU patients.The onset of peptic ulcers is seasonal,mostly in spring.The number of sick people in spring and winter is more than the total number of people in summer and autumn.The average course of patients was 87.22 + 125.444 months,about 7.3 years;the patients with the course of 1-10 years were the most,and the patients with the course of disease for more than 20 years were the least.2 Causes and distribution of diseaseIn this study,there were 46 smokers,including 43 men,3 women(P<0.05),smoking ratio was 14.33:1,and 31 patients drank alcohol,including 30 men and 1 women(P<0.05).It is suggested that smoking and drinking may be associated with the incidence of PU.53.3% of the patients had no obvious inducement,other incentives including diet,cold,emotion,drugs etc..It is mainly related to diet and emotion.The positive rate of Hp infection was 62.4%,the positive rate of Hp in GU patients was 52.1%,the positive rate of Hp in DU was 76%,and the positive rate of Hp in CU patients was 47.1%.It is higher than the general population.The positive rate of Hp in male patients was 69.4%,and the positive rate of Hp in female patients was 49.1%(P<0.05),and the positive rate of male was higher than that of women.The number of Hp positive patients at the age of 51-60 was the most.With the increase of age,the infection rate of Hp is more and more high,at the age of less than 40 year old patients with positive rate of Hp is: 43.5%,the positive rate of Hp at the age of 41-50 year old patients is 56.7%,the positive rate of Hp at the age of 51-60 year old patients is 59.3%,the positive rate of Hp at the age of 61-70 year old patients is: 77.4%(P<0.05)。The positive rate of GU is 52.1%,DU was 76%,CU is 47.1%(P<0.05)。The positive rate of different TCM Syndromes of Hp infection from high to low is: liver and stomach heat stagnation type(85.7%)> Dampness-heat in the spleen and stomach type(64.35%)> Liver stomach disharmony type(57%)> deficiency of spleen and stomach(deficiency-cold)type(38.5%),(P<0.05).3 Clinical manifestationsIn this study,111 patients had symptoms of upper abdominal distension and pain(67.3%),while 126 patients received upper abdominal tenderness for 76.4% when they were examined by doctors.In 11 cases,the stomach pain was more obvious on the empty stomach and at night.The symptoms of abdominal pain as the main clinical manifestations of PU patients,accompanied by belching,acid regurgitation,anorexia,dry mouth,change in bowel habit symptoms.4 TCM syndrome type of peptic ulcerThe cluster analysis of 5 groups of symptoms from more to less as follows:liver stomach disharmony type(60cases)>liver and stomach heat stagnation type(34cases)>Dampness-heat in the spleen and stomach type(31 cases)>deficiency of spleen and stomach(deficiency-cold)type(21 cases)>Liver stagnation and spleen deficiency type(19 cases)In this study the syndrome rate from high to low as follows: liver stomach disharmony type(47.9%)>liver and stomach heat stagnation type(38.5%)> deficiency of spleen and stomach(deficiency-cold)type(15.8%)> Dampness-heat in the spleen and stomach type(8.5%)> stomach yin deficiency type(1.8%)> blood stasis resistance gastric collaterals type(0.6%)In liver stomach disharmony type,liver and stomach heat stagnation type,the number of DU patients was more than that of GU,more than that of CU.In the liver and stomach heat stagnation type,deficiency of spleen and stomach(deficiency-cold)type,the number of patients with GU more than DU,more than CU.In the Dampness-heat in the spleen and stomach type,deficiency of spleen and stomach(deficiency-cold)type patients,the difference was statistically significant.5 Treatment according to syndrome differentiationIn this study,the main idea is to adjust Qi and strengthen the spleen,eliminate carbuncle and relieve pain.At the same time,using the method of supplement and discharge,balance the cold and heat of the patient’s body,at the same time treat other viscera,take the patient as the center,flexibly increase or reduce the drug.This method of treatment can achieve good curative effect.Conclusion: 1.The age of patients with DU is earlier than that of GU,and PU often occurs in winter and spring,and the course of this disease is long.PU patients are more male than women,which may be related to men’s living habits(smoking,drinking),high Hp infection rate,and working pressure.Diet,the mood of the patient is the common cause of the disease.2.In terms of Hp infection rate,DU patients were higher than GU patients,and the higher the age was,the higher the infection rate.In liver and stomach heat stagnation type and dampness-heat in the spleen and stomach type,the infection rate was significantly higher than other syndromes,which is consistent with the "heat toxic" theory.It has some guiding significance for clinical research.3.The main clinical symptoms of patients with peptic ulcer is often accompanied by abdominal pain,belching,acid regurgitation,anorexia,dry mouth,red tongue,the coating on the tongue is thin and white or thin yellow,pulse string pulse is.4.The most common type is liver stomach disharmony,followed by liver and stomach heat stagnation type.In the dampness-heat in the spleen and stomach type,the number of DU patients is more than that of GU,more than that of CU.In the deficiency of spleen and stomach(deficiency-cold)type,the number of GU patients is more than that of DU and more than CU.5.In the treatment,it is important to adjust Qi and invigorate the spleen,eliminate carbuncle and relieve pain.Take the patient as the center,to add or reduce drugs flexibly. |
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