Observation On The Clinical Efficacy Of The Method Of Removing Phlegm And Clearing Heat In The Treatment Of Insomnia With Internal Disturbance Of Phlegm-heat

Purpose:To observe the effect of resolving phlegm and clearing heat method on insomnia of phlegm-heat internal disturbance type,and to explore its effectiveness and safety.Research method:1.Objectives: 60 cases of insomnia with phlegm-heat disturbance in cardiology outpatient department were selected as the research object.2.Methods: 60 subjects were randomly divided into treatment group(30 cases)and control group(30 cases).The patients in the treatment group were treated with Huanglian Wendan Decoction plus or minus one dose a day,while the patients in the control group were treated with Wenfei(right zopiclone)once a day for 3mg.The treatment course of both groups was 4weeks.The treatment group and control group were compared before and after self-treatment and 4 weeks after treatment.The clinical therapeutic effect was observed before and after treatment by PSQI score and TCM Syndrome Scale score.Statistical soft ware SPSS 20.0 is used to analyze all experimental data.Results:1.The Pittsburgh Sleep Quality Index(PSQI)score: before treatment,the treatment group(14.77 ± 1.87),after treatment(6.00 ± 2.10),P=0.00(<0.05),indicating a significant difference before and after treatment;in the control group,before treatment(14.70±1.95),after treatment(6.93±2.30),P=0.00(<0.05),there was a significant difference before and after treatment.The results showed that both groups could significantly reduce the Pittsburgh Sleep Quality Index score.After treatment,there were significant differences in sleep quality and sleep time,between the two groups(P<0.05),indicating that the therapeutic effect of the treatment group was superior to that of the control group in these two factors,but there were no significant differences in sleep time,sleep efficiency,sleep disorder,hypnotic drugs and daytime dysfunction.2.The scores of TCM Syndrome Scale: before treatment,the treatment group(16.43±2.03),after treatment(3.97±1.61),P=0.00(<0.05),there were significant differences before and after treatment;in the control group,before treatment(16.27±1.64),after treatment(5.33±1.56),P=0.00(<0.05),there were significant differences before and after treatment.It showed that both groups could significantly improve the symptoms of insomnia(P<0.05).After treatment,the P values of sleeping disturbance,chest tightness,distress and chagrin,phlegm in bitter mouth,pulse slippery or slippery number and greasy moss in the two groups were all less than 0.05,which showed that the treatment group had better effect than the control group in the above six aspects.3.There were no abnormal changes in blood,urine,stool routine,electrocardiogram,liver and kidney function and no adverse reactions during the treatment of the two groups.Conclusion:1.The method of resolving phlegm and clearing heat has better curative effect on insomnia patients with phlegm-heat internal disturbance.It can not only improve the TCM syndromes of phlegm-heat internal disturbance,but also reduce the Pittsburgh sleep quality index.2.The method of resolving phlegm and clearing heat has good safety in treating insomnia with phlegm-heat internal disturbance.