Clinical Observation Of Huanglian Wendan Decoction On Treating Insomnia With Syndrome Of Phlegm-heat Disturbance Of The Heart

Objective:The purpose of this by observing the effect of HuanglianWendan decoction on treating the phlegm-fire type of insomnia,it provides theoretical support for further flexible and accurate clinical syndrome differentiation.Methods:Sixty patients with the phlegm-fire type of insomnia were selected from February 2019 to March 2020 in the outpatient department of neurology of the first affiliated Hospital of Hunan University of traditional Chinese Medicine.Two groups were randomly divided into two groups:the treatment group(n=30)and the control group(n=30).The treatment group was treated with Huanglian Wendan decoction,while the control group was treated with Eszopiclone.Observe the Pittsburgh sleep scale(PSQI)before and after treated、TCM symptom score、the changes of the safety index and the presence of adverse reactionsResults:(1)before treatment,there was no significant difference in age、gender、course of disease between the two groups(P>0.05).(2)After treatment,both groups had similar effect on the improvement of PSQI(P>0.05),while the effect of TCM syndrome improvement is remarkable,and the treatment group had higher effect(P<0.05).(3)there were no adverse reactions in the treatment group and the control group during the treatment period.The results suggest that both drugs are safe.Conclusion:Huanglian Wendan decoction is significantly effective in treating the phlegm-fire type of insomnia,the efficacy of the Pittsburgh sleep scale(PSQI)was similar to that of the control group,while the comprehensive efficacy of TCM syndrome score was better than that of Eszopiclone group,improving the quality of life patients,clinical medication safety,and no adverse events.