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Angiographic Examination And Analysis Of Risk Factors In Patients With Acute Coronary Syndrome After Coronary Artery Bypass Graft Surgery

Posted on:2021-01-24Degree:MasterType:Thesis
Country:ChinaCandidate:Y Y LiFull Text:PDF
GTID:2434330611993733Subject:Clinical Medicine
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Objective: Through the retrospective analysis on clinical data and characteristics of bridge arteriography in patients with the coronary artery bypass grafting,this study aims to investigate the characteristics of the cardiac allograft vasculopathy and related cardiovascular risk factors to make an early detection,anticipation and identification on risk factors to reduce the incidence of the posoperativeacute coronary syndrome and providereference for clinical diagnosis and effective treatment.Methods: A retrospective collection was made of 280 cases of CAG from Qingdao Starr heart hospital who had chest pain and other discomfort after CABG operation between January 2006 and October 2016.The study group included 160 patients with acute coronary syndrome and the control group included 120 patients.At the same time,the selected study subjects all met the inclusion criteria and had characteristics such as characteristic chest pain,electrocardiogram changes,and elevated serum myocardial markers.The patients in the group were tested for blood platelet parameters,fibrinogen,D-dimer and other related biochemical indicators;the patients in the group were all subjected to coronary angiography,and the bridge vessel was completely occluded or narrow.Results: Compared with the control group,the variables of age and gender were not statistically significant in patients with CAG after recurrence of angina pectoris after CABG recurrence.The BMI of the study group was significantly higher than that of the control group,reaching 25.07 ± 3.03.The difference was extremely significant(P <0.01);the resting heart rate in the study group was significantly higher than that of the control group,76.20 ± 8.36,the difference was statistically significant(P <0.01);the patients in the study group had a history of smoking,hypertension,The proportions of diabetes history and family history of coronary heart disease were more than that of the control group,the differences were significant(P <0.05),and it was statistically significant;the MPV in laboratory indexes of patients who were admitted to the hospital for CAG after relapse of angina pectoris after CABG was 11.63 ± 1.93,significantly higher than the control group(8.82 ± 1.60),the difference between the two was very significant(P <0.01),with statistical significance;the TC index of the study group was 4.33 ± 1.62,higher than the control group(3.58 ± 0.79),the difference was significant(P <0.05);The LDL-c index of Study group was 3.38 ± 1.51,FIB index was 3.55 ± 1.21,DD index was 0.89 ± 0.82,HCO3-index was 29.83 ± 1.77,that was higher than the control group,the differences were significant(P <0.05);HDL-c index of the study group 1.22 ± 0.08,lower than the control group(1.68 ± 0.03),the difference was significant(P <0.05);but the PDW?PLT?PCT?TG?UA and Cys C in the laboratory indicators were not significant compared with the control group,No statistical significance.History of hypertension,MPV,FIB,and HCO3-were the risk factors for CAG after relapse of angina pectoris after CABG;AO-SV(RA,RIMA)-blunt margin The highest was 56.07%,of which the occlusion reached 39.25%,and the stenosis ?75% reached 16.82,and the lesion rate of LIMA-anterior descending branch was the lowest,18.11%,of which,the occlusion rate was 9.45%,and the ratio of stenosis ?75% was 8.66%;When the interval between CABG and CAG was more than 10 years,the SV bridge disease rate and LIMA bridge disease rate were the highest,66.13% and 25.00% respectively;within 1 year,1 to 5 years and 6 to 10 years With the extension of the interval between CABG and CAG,the disease rate of LIMA bridge showed a decreasing trend.When the interval time was more than 10 years,the disease rate of LIMA bridge increased;the disease rate of SV bridge between CABG and CAG was 1 within the year,between 1 and 5 years,between 6 and 10 years,and above 10 years,it showed a law of increasing year by year,and the growth rate was stable.Conclusion: In clinical practice,clinicians should pay more attention to the risks on patients with acute coronary syndrome after coronary artery bypass surgery,attach great importance to angiography and risk factor analysis,attach great importance to BMI value,resting heart rate,smoking history,hypertension history,diabetes history,and coronary heart disease Family history,MPV,TC,FIB,HCO3-are closely related to the occurrence of acute coronary syndrome in patients after coronary artery bypass surgery.LIMA-anterior descending branch is the bridge vessel with the highest patency rate and can be used clinically.Therefore,active prevention and treatment of acute coronary syndrome after coronary artery bypass surgery can avoid the occurrence of complications,reduce the risk of cardiovascular death and improve the quality of the patients' life.
Keywords/Search Tags:Coronary artery bypass grafting, Coronary angiography, Cardiovascular risk factor
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