Study On TCM Syndrome Of Metabolic Syndrome Patients With Type 2 Diabetes

Purpose:Through the investigation of 246 patients with metabolic syndrome accompanied with type 2 diabetes mellitus,To explore the distribution characteristics of common clinical TCM syndromes in patients with metabolic syndrome with type 2 diabetes,and to analyze the statistical results of relevant factors,to further explore the distribution characteristics of common syndromes and the correlation with physical and chemical factors,so as to provide some reference for the clinical syndrome differentiation and treatment and prevention of the disease.Material and method:From January 1,2019 to December 31,2019,all patients in the Department of Endocrinology,Affiliated Hospital of Liaoning University of traditional Chinese medicine were included in this study.315 cases were diagnosed as type 2 diabetes and metabolic syndrome,and 246 complete cases were obtained excluding incomplete clinical data collection.The distribution of syndrome types,the combination of each component,gender,age,course of disease,smoking history,drinking history,UA,EGFR and ACR of the patients were analyzed to explore the distribution characteristics of common syndrome types and the correlation with various physical and chemical factors.Results:1.According to the expert’s syndrome differentiation and scoring,the selected metabolic syndrome patients with type 2 diabetes mainly involve the syndrome of deficiency of Qi and Yin,the syndrome of combination of phlegm and heat,the syndrome of excessive heat and injury of body fluid,the syndrome of stagnation of blood stasis and the syndrome of deficiency of yin and Yang.2.The distribution frequency of the involved syndrome types is from high to low: Qi Yin deficiency syndrome(35.8%),phlegm heat syndrome(31.7%),blood stasis syndrome(13.0%),heat injury syndrome(12.6%),yin yang deficiency syndrome(6.9%).3.The Syndrome types of different components have different distribution characteristics:phlegm-heat Syndrome is most common in patients with hyperlipidemia,qi-yin Deficiency Syndrome is most common in patients with hypertension,and qi-yin Deficiency Syndromeand phlegm-heat Syndrome are most common in patients with hyperlipidemia and hypertension.However,no matter how the composition changes,yin-yang Deficiency Syndrome are the least.4.The relationship between gender,age,course of disease and syndrome type: there is no difference in gender among syndrome types;the age of phlegm heat syndrome is the smallest,and the age of yin yang deficiency syndrome is the largest;in the course of disease,the course of yin yang deficiency syndrome is the longest,and the course of phlegm heat syndrome is the shortest.5.The relationship between smoking,drinking and syndrome type distribution: there was no correlation between smoking history and syndrome type distribution.There was significant difference in drinking history between syndrome types.The number of drinking in phlegm heat syndrome was significantly higher than that in Qi Yin deficiency syndrome(P < 0.05).6.There was no significant difference in UA level among different TCM syndrome groups(P > 0.05);EGFR level was the lowest in stasis syndrome and the highest in heat hyperactivity injury syndrome;ACR was higher in yin-yang deficiency syndrome and Qi Yin deficiency syndrome,while phlegm heat combination syndrome and heat hyperactivity injury syndrome were lower;Conclusion:1.The common syndromes of metabolic syndrome with type 2 diabetes in Liaoshen area are Qi Yin deficiency,phlegm heat combination,blood stasis and internal stasis,heat hyperactivity injury and Tianjin syndrome,and Yin Yang deficiency.Among them,Qi Yin deficiency syndrome and phlegm heat syndrome are the most common.2.The different components of Metabolic Syndrome are different in the distribution of different syndrome types.3.There was no significant difference in gender,smoking history and serum uric acid level among different syndrome types.4.Age,course of disease,drinking history,EGFR level and ACR level are correlated with syndrome types,which can be used as an important objective reference for clinical syndrome differentiation.