| Objective:in this paper,the hardening of the arteries crowd for 16 weeks of tai chi exercise intervention,to observe 16 weeks after the intervention subjects baPWV,blood lipid,uric acid,asymmetric dimethylarginine,endothelin and the change of inflammatory factors and related indicators,analysis of taijiquan exercise on arteriosclerosis crowd control effects of taijiquan exercise on lower arterial hardness,prevent delay the influence mechanism mechanism of atherosclerosis,make the taijiquan movement more popular,improve the level of residents'physical health,prevent the happening of the cardiovascular disease development.Methods:in this study,46 people(10 males and 36 females)with baPWV abnormality were screened out from lan zhuang community,with an average age of 52.41±2.30 years old.Before the intervention,the exercise group measured target rate of each subject,and administered moderate intensity taijiquan for 5 days/week and 1 hour/day.Subjects before the experiment the movement was detected in 16 weekend's height weight,body fat rate,baPWV,ABI,such as physiological indexes,uric acid,blood lipid(total cholesterol,triglycerides,high-density lipoprotein cholesterol,low density lipoprotein cholesterol),endothelial factor(asymmetry dimethyl arginine,nitric oxide,endothelin-1),inflammatory factor(tumor necrosis factor alpha,matrix metalloproteinases-9)and other biochemical indicators.Results:(1)at the weekend of exercise 16,baPWV of the left and right sides of the exercise group decreased significantly(P<0.05)and ABI decreased significantly(P>0.05),but there was no significant difference between the two groups.(2)at the end of 16 weeks of exercise,uric acid in the exercise group decreased significantly(P<0.05),and there was significant difference between the exercise group and the control group in the posttest(P<0.01),while there was no significant change in the control group before and after the experiment.(3)at the weekend of exercise 16,TC and ldl-c in the exercise group decreased significantly(P<0.05),hdl-c increased significantly(P<0.01).TG did not change significantly(P>0.05),and no significant changes were observed in the control group before and after the experiment.(4)at the weekend of exercise 16,both ADMA and et-1 in the exercise group decreased significantly(P<0.01),and NO increased significantly(P<0.01).Comparing between the two groups,NO in the exercise group was significantly different from that in the control group(P<0.01).NO significant changes were observed in the control group before and after the experiment.(5)at the weekend of exercise 16,TNF-and mmp-9 in the exercise group were significantly decreased(P<0.01),and significant differences were observed between the exercise group and the control group(P<0.01).No significant changes were observed in the control group before and after the experiment.(6)at the weekend of exercise 16,baPWV was positively correlated with UA(r=0.287,P<0.05)and negatively correlated with hdl-c(r=-0.274,P<0.05).Conclusion:16 weeks of taijiquan exercise showed that:(1)16 weeks of taijiquan exercise can significantly reduce the baPWV of atherosclerosis population and reduce the degree of vascular stiffness,taijiquan exercise can be used AS an effective means of prevention and treatment of AS.(2)16 weeks of taijiquan exercise can reduce TC and ldl-c levels,increase hdl-c levels,reduce cholesterol deposition.effectively improve blood lipid status,prevent and alleviate the occurrence and development of AS in atherosclerosis population.(3)for 16 weeks,taijiquan can effectively reduce UA,ADMA,NO and et-1 levels in atherosclerosis patients,reduce endothelial injury and improve vascular endothelial status.(4)16 weeks of taijiquan exercise can effectively reduce the levels of serum inflammation TNF-and mmp-9 in atherosclerotic people,thereby reducing the inflammatory response of the body and protecting the endothelium,which can be used AS one of the mechanisms of taijiquan exercise to prevent AS. |
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