| Diabetes is one of the leading causes of death and disability in the world,and blood sugar detection is an important subject.Abnormal glucose levels in the body's blood can lead to diseases such as blindness,neurodegeneration and kidney failure.These complications can lead to retinopathy,retinopathy can lead to blindness,kidney disease can lead to kidney failure,peripheral nerve injury,and increase limb(foot)ulcers,amputation,cardiovascular disease and even cancer risk.Since the medical profession has not yet developed an effective method to cure diabetes,abnormal blood glucose levels are associated with many diseases,including celiac disease,cystic fibrosis,tuberculosis,and heart disease.These complications can lead to retinopathy,which can lead to blindness?kidney disease can lead to kidney failure?peripheral nerve damage?and increase the risk of limb(foot)ulcers?amputation?cardiovascular disease and even cancer.Since the medical profession has not yet developed an effective method to cure diabetes,it is necessary to accurately monitor and control the glucose level in the body so as to reduce the obstacles and effects of diabetes on the life of the human body.Currently,people's demand for wearable glucose sensors is increasing.Therefore,this article uses carbon fiber fabric(CFT)and polyurethane(PU)as the substrate,and cobalt phthalocyanine(CoPc)and carbon nanotube(CNT)in different proportions as catalysts.Different flexible non-enzymatic glucose sensors.To characterize its performance,the specific research content and results are as follows:(1)CoPc/CNT/CFT non-enzymatic glucose sensor based on CoPc/CNT loaded on carbon fiber fabricIn this study,this paper used the strong?-?interaction between cobalt phthalocyanine(CoPc)and carbon materials to load it on the carbon nanotubes.CoPc is a good electrocatalytic active material that can electrocatalyze oxidized glucose.In this paper,CoPc/CNT/CFT was directly made into an independent working electrode,without additional electrodes or adhesives.The prepared CoPc/CNT/CFT was characterized by SEM(Scanning Electron Microscope)technology.Optimized the ratio of CoPc/CNT,electrolyte concentration and measurement potential.Electrochemical methods(AC impedance spectroscopy,cyclic voltammetry curve,time-current method)were used to analyze the performance of the CoPc/CNT/CFT electrode for direct electrocatalytic oxidation of glucose.In addition,the stability and anti-interference performance of CoPc/CNT/CFT were tested experimentally.The results showed that the linear detection range of the CoPc/CNT/CFT electrode for glucose was 4×10-3-2.6 m M,the detection limit could be as low as 1.4?M(signal-to-noise ratio=3),and the sensitivity is 231?A·m M-1.The CoPc/CNT/CFT modified electrode had good repeatability and stability when detecting glucose,and had strong anti-interference performance against the corresponding interference.Moreover,the sensor was used to detect the glucose content in the actual human sweat,and the result is consistent with The commercial instruments are the same.(2)CoPc/CNT/PU non-enzymatic glucose sensor based on CoPc/CNT loaded on PU nanofiber membraneWearable sensors need to have better skin affinity and elasticity,which carbon fiber cloth cannot provide.Therefore,in the second part of this study,PU nanofiber membranes were prepared by centrifugal electrospinning method based on PU.And through condensation reflux,the dispersion of CoPc on the CNT is more uniform.Next,the CoPc/CNT/PU was directly made into an independent working electrode without additional electrodes or adhesives.TGA(thermogravimetric analysis)was used to characterize the prepared CoPc/CNT,and SEM technology was used to characterize and analyze the CoPc/CNT/PU.Optimized electrolyte concentration and measurement potential.The electrochemical method(AC impedance spectroscopy,cyclic voltammetry curve,time-current method)were used to analyze the performance of the CoPc/CNT/PU electrode for direct electrocatalytic oxidation of glucose.Detect the content of glucose in real human sweat with CoPc/CNT/PU electrode.In addition,the stability,repeatability and anti-interference performance of CoPc/CNT/PU were tested experimentally.The results showed that its linear detection range for glucose is 5×10-3-4.1 m M.The detection limit could be as low as 3.2?M(signal-to-noise ratio=3),and the sensitivity was248?A·m M-1.After 30 days of repeated testing,the current response of the CoPc/CNT/PU electrode to glucose could still reach 85.4%of the initial value.It had good repeatability and stability,and had strong anti-interference performance against interfering substances.The sensor was used to measure the glucose content in human sweat,and the results were consistent with commercial instruments.This showed that the glucose sensor could accurately detect the glucose concentration in human sweat. |
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