The Research On The Construction Of Responsive Metal-organic Framework Material And Their Optical Sensing Application

Metal organic frameworks(MOFs)are assembled by metal ions/clusters and organic linkers,which have attracted remarkable attention because their high porosity,tunable and stable structures andlarge surface areas.Compared with traditional porous materials,MOFs have been applied in many fields,such as separation storage,catalysis,sensing,biomedicine and so on.Especially in the field of sensing,MOFs materials are superior to other candidate chemical sensing materials due to their catalysis,luminescence,magnetism and selective adsorption functions,and have been widely used to construct analytical sensors.Therefore,the rational design of MOFs materials play a vital role in expanding the development of sensing.This paper is aim to rationally construct responsive MOFs with specific functional sites,which are employed to develop optical sensors to expand the application of MOFs in analytical sensing.The main research contents are as follows:Chapter 1 OverviewThis chapter is mainly about the advantages of MOFs materials,synthesis methods and their applications in various fields,and the content and significance of the research carried out in this paper are described.Chapter 2 Functionalized iron-based metal organic framework materials with peroxidase mimetic properties for visual detection of fluoride ionsIn this paper,we use 3,5-dicarboxyphenylboronic acid as the linker to prepare Fe-NMOFs by a simple solvothermal method for the first time.The as-obtained Fe-NMOFs possess excellent peroxidase-like activities.The peroxidase-like activity of Fe-NMOFs was effectively inhibited by fluoride ion owing to the specific recognition between the boronic acid groups and fluoride ion along with the strong binding affinity between Fe³⁺and fluoride ion.In view of this,we have prepared it into a portable kit for fast,easy-to-operate and visual detection of F^-in water samples.This method has a linear range of visual detection of F^-between 10.0-200?M and a detection limit of 1.5?M,which is superior to many existing detection methods.Chapter 3 A lanthanide metal organic framework-based ratiometric fluorescent probe for the detection of anthrax biomarkerIn this paper,a novel lanthanide metal organic framework(Eu-MOFs)is self-assembly with 4-amino-isophthalic acid as a ligand and the rare earth ion Eu³⁺as metal ion.The Eu-MOFs have blue fluorescence emission based on the organic ligands.When anthrax biomarker(DPA)is added,DPA molecules can transfer the energy to Eu³⁺,Eu-MOFs appear Eu³⁺characteristic fluorescence peaks.At the same time,the fluorescence of the ligand is basically unaffected.In view of this,this paper has developed a ratiometric fluorescent probe for DPA detection based on fluorescence enhancement with high selectivity and sensitivity.The detection linear range of this method for DPA is between 0.1-10?M,and the detection limit is 47.5n M.This system has been successfully used for the detection of DPA in actual samples.