Preliminary Application Study Of Chemical Sensor Method For Detecting Copper And Oxcarbazepine Based On The Principle Of Molecular Recognition

With the continuous mining and application of copper ore,copper ions(Cu²⁺)are easily accessible to the environment and cause pollution during production and utilization.As the third essential trace element in the human body,copper ions play an important role in the body’s physiological process,but excessive intake of Cu²⁺can also cause shock and even death in the body.Oxcarbazepine（OXC）,a new type of anti-epileptic drug.Patients with overdose of the OXC may experience symptoms such as dizziness,headaches,and coordination disturbances.Therefore,the development of chemical sensors for detecting Cu²⁺and OXC has attracted people’s attention.Although the existing detection methods can accurately detect the above two substances,the instruments used are difficult to apply to actual detection.Fluorescence analysis and electrochemical analysis are widely used in the field of analysis and detection due to their easy operation and low cost.In this paper,a macrocyclic Schiff base fluorescent chemical sensor for identifying Cu²⁺and a magnetic molecularly imprinted electrochemical sensor for detecting the OXC are designed.The specific content is as follows:Part 1:The article firstly introduces the importance of Cu²⁺and the OXC and the research progress of its analysis and detection,and then explains the working principle of chemical sensors,the overview of Schiff base fluorescent chemical sensors and the application progress of different fluorescent chemical sensors to detect Cu²⁺.Then introduced the principle of molecular imprinting technology,the classification of molecular imprinted electrochemical sensors,the application of Fe₃O₄nanoparticles in molecular imprinted electrochemical sensors and the application progress of different methods to detect the OXC.Part 2:A new method for detecting Cu²⁺in aqueous medium isconstructed based on the macrocyclic Schiff base fluorescent chemical sensor BP-MSB.The changes in the optical properties of BP-MSB coordinated with metal ions under optimal conditions show its high selectivity to Cu²⁺.Based on this,it has been successfully applied to detect Cu²⁺in environmental water samples.Part 3:This article prepares an electrochemical sensor MNPs-MIP/MCPE for detecting the OXC.The experiment is based on the sensor’s differential pulse voltammetry（DPV）to detect the OXC in samples.In the range of the OXC concentration of 50.0 n M～0.15 m M,the DPV method of the MNPs-MIP/MCPE sensor to detect the OXC has a good linear relationship and shows excellent recognition performance.In addition,the sensor successfully detects actual samples.Part 4:We summarizes the advantages and disadvantages of the chemical sensors prepared in the article,as well as the follow-up aspects that need to be improved,and prospects the development of chemical sensors.