Fabrication Of Non-enzymatic Glucose Electrochemical Sensor Based On Nickle-molybdenum-base Carbon Nanofibers

Glucose is an important energy substance in the body,and its concentration in the body is a reflection of the health status of the body.In pathological conditions,such as diabetes patients,glucose is abnormally elevated,so the detection and treatment of diabetes is extremely urgent.Therefore,the establishment of fast accurate low cost and high sensitivity of the sensor is a top priority in the field of glucose sensing.In recent years,the emergence of all kinds of new type of structure and morphology of nanometer materials and carbon materials and their compound based on various nanostructures has been developed for glucose detection.Furthermore,nanometer materials with high conductivity larger surface area and unique performance advantages,provides more active site,which can significantly improve the feasibility of the electrolyte into the active sensor surface.This paper has important practical reference value for the study of non-enzymatic glucose sensor,the following two aspects have been studied:1.The porous carbon nanofibers（NiMoO₄-CNF）were prepared by carbonization of the products synthesized by electrospinning.Electrochemical measurements showed that NiMoO₄-CNF contributed to the oxidation of glucose and the signal amplification reaction.The porous carbon nanofibers and the well-encapsulated active component of Ni-Mo₂C enhanced the electrocatalytic stability.Ni MO₄-CNF exhibited good catalytic activity against glucose,with low response potential（0.45 V）,high sensitivity(193μA?mmol/（L?cm²）,linear response region of 0.01-7 mmol/L,low detection limit（4.5μmol/L）and rapid response time（2 s）.NiMoO₄nanofibers are not only beneficial to electron transfer,but also can mediate the electrocatalysis of glucose reaction.It can effectively promote the electrocatalytic oxidation of glucose and reduce the oxidation potential of glucose through signal amplification.2.In this study,Ni and NiMoO₄nanorods doped polyvinyl alcohol（PVA）carbon nanofibers were prepared by electrospinning.The two precursors were carbonized to obtain Ni-CNF and Ni-Mo₂C-CNF composites.The direct electrocatalytic activity of Ni-CNF and Ni-Mo₂C-CNF for glucose was investigated by characterizing the composition and morphology of the prepared materials.The results showed that both Ni-CNF and Ni-Mo₂C-CNF exhibited good electrocatalytic activity for glucose,including low response potential（0.45 V）and high sensitivity（198u A?mmol/（L?cm²））,wide linear range（0.01-7 m M）,low detection limit（4.3μmol/L）,and the non-enzymatic glucose sensor has good reproducibility,stability and selectivity.This study provides a theoretical basis for electrocatalytic non-enzymatic glucose sensor using nickel-based carbon nanofibers as catalyst,and has important practical reference value.