Analysis Of The Short-term Effect Of The Modified New Sandwich Method On Esophageal And Gastric Variceal Bleeding

Objective: To explore the short-term efficacy and safety of the modified new sandwich method in the treatment of esophageal and gastric variceal bleeding.Methods: A total of 130 cirrhotic patients with esophageal-gastro varices bleeding who were admitted to The Second Nanning People’s Hospital were collected and retrospectively analyzed.All patients were first treated under gastroscope within 72 hours after admission.According to different treatment methods,they were divided into two groups.Control group(traditional treatment group): from December 2014 to September 2017,62 cases of esophageal and gastric varices bleeding were treated with traditional sandwich method(lipiodol-tissue glue-lipiodol);observation group(modified treatment group): from October 2017 to October 2019,68 cases of cirrhosis with esophageal and gastric varices bleeding were treated with modified new sandwich method(lauromacrogol-tissue glue-air-normal saline).The operation time,tissue glue dosage,hemostasis success rate,early rebleeding rate,late rebleeding rate,adverse reaction rate,postoperative varicose rate,improvement rate and mortality rate of varicose veins were observed.Results:(1)The difference between the observation group and the control group was statistically significant(P<0.05);(2)the success rate of hemostasis in the observation group was 100%,the success rate of hemostasis in the control group was 91.94%,the difference was statistically significant(P<0.05);(3)the early rebleeding rate of the observation group was 5.88%,the early rebleeding rate of the control group was 19.35%,the observation group was significantly better than the control group,the difference was statistically significant(P<0.05);(4)The rate of delayed rebleeding was 7.35% in the observation group and12.90% in the control group,with no significant difference(P>0.05);(5)The incidence of adverse reactions was 16.18% in the observation group and 22.58%in the control group.There was no statistical difference in the incidence of postoperative adverse reactions between the two groups(P>0.05).(6)one month after the operation,the effective rate and improvement rate of varicose veins were 51.47% and 80.88% in the observation group,and 33.87% and 53.23% in the control group,respectively,with statistically significant differences(P<0.05).(7)six months after the operation,there was no statistical difference in the mortality rate between the two groups(P >0.05).Conclusion: Compared with the traditional sandwich method,the modified new sandwich method has the advantages of high success rate of hemostasis,low rate of early rebleeding and effective improvement of esophagogastric varices which is safe and worthy of further clinical study.