The Value Of Contrast Enhanced Ultrasound Endoscopy In Differentiating The Solid Space-occupying Properties Of The Pancreas

Objective Contrast the imaging manifestations of contrast enhanced ultrasoundendoscopy(CE-EUS)in various types of specific chronic pancreatitis and pancreatic cancer,and analyze the value of contrast enhanced ultrasound endoscopy in its differential diagnosis.Methods Collected in July 2014-January 2020,the First Affiliated Hospital of Guangxi Medical University were the pancreas line type solid focal lesions and contrast enhancement cases of endoscopic ultrasonography in all 32 cases,chronic pancreatitis(CP)in 7 cases,autoimmune pancreatitis(AIP)in 5 cases,4cases of focal mass type pancreatitis(MFP)and pancreatic cancer(PC)in 16 cases,in each case patients were CE-EUS examination,for various types of special CE-EUS video characteristics of pancreatitis and pancreatic cancer patients were analyzed.Result Thirty-two patients with solid pancreatic space occupation were examined by contrast enhanced ultrasound endoscopy and eus-fna,and the final diagnosis was determined by pathological type.According to pathological classification,it was divided into two groups,specifically benign lesion group and malignant lesion group.The benign lesion group included three pathological types: chronic pancreatitis,autoimmune pancreatitis and mass pancreatitis.All the malignant lesions were pancreatic cancer.There was no significant difference in gender between the benign lesion group and the malignant lesion group,and the mean age of the benign lesion group was lower than that of the malignant lesion group(P<0.05).The diagnosis rates of solid pancreatic space occupying by abdominal B-ultrasound,CT,MRI/MRCP and CE-EUS were 18.8%,63.0%,50.0% and 90.6%,respectively.Benign lesions and malignant lesions of contrast enhancement pattern,enhance strength,enhance the difference between the opposite sex analysis by the chi-square test P < 0.05,there is statistical significance,and there was no significant difference in the time-intensity difference of contrast agent between benign and malignant lesions(P>,0.05).Chronic pancreatitis with special type of chronic pancreatitis,contrast enhancement pattern,enhance strength,enhance the difference between the opposite sex analysis by the chi-square test P < 0.05,there is statistical significance,There was no significant difference in the time-intensity variation of contrast media(P>,0.05).For MFP and AIP of both special types of chronic pancreatitis,the difference in the intensity of contrast enhancement was analyzed by chi-square test(P<0.05),which was statistically significant,and there was no significant difference in the mode,phase and time-intensity of enhancement(P>,0.05).Conclusion CE-EUS differential diagnosis of pancreatic cancer and chronic pancreatitis was higher than that of transabdominal ultrasound,CT,MRI/MRCP.Different pancreatic lesions have different characteristics of contrast enhancement.CE-EUS is of great value in the identification of pancreatic solid space occupying properties.