| BackgroundSurgical incisions can be divided into four types: Ⅰ,Ⅱ,Ⅲ and Ⅳ.At present,most surgical incisions are Ⅱ.Surgical incision infection is a common complication in clinical practice,which accounts for 25% of all surgical infections.Currently,antibiotics are routinely used to prevent infection before Class Ⅱ incision surgery;Postoperative wound infection requires etiological examination and drug sensitivity identification,but a certain amount of time to wait for the results of drug sensitivity,during which the majority of drug use depends on the experience of clinicians.Therefore,it is necessary to analyze the pathogenic characteristics and drug sensitivity of postoperative infection of Class Ⅱ surgical incision in order to obtain the results of common bacteria and drug sensitivity,and to provide relevant scientific basis for clinical application of antibiotics.ObjectiveTo analyze the etiological investigation of postoperative infection in patients with Class Ⅱ surgical incision in general surgery,and to study the drug resistance in general surgery,according to the analysis results to guide the clinical use of antibiotics,and reduce postoperative incision infection rate.MethodWe selected 27 patients from the First Affiliated Hospital of the Xinxiang Medical University who underwent surgery from January 2016 to December 2017 with Class Ⅱ incision infection.The data of bacteria culture and other related materials were collected,and the results of pathogenic bacteria and drug sensitivity were analyzed statistically.The wound bacteria were cultured in patients with wound infection after Class Ⅱ surgical incision,and the specimens were collected,then the pathogen was clutivated,isolated,identified and drug sensitivity tested.The BD Phoenix M50 automatic microbial identification drug sensitivity analysis system was used,in which Oxoid paper was used for k-b method drug sensitivity test,the results of drug sensitivity test were determined according to the 2017 Clsi M 100-s 27 standard,and the results were compared with those of standard strain Staphylococcus aureus ATCC 25923,escherichia coli ATCC 25922 and pseudomonas aeruginosa ATCC 27853.The collected original records are kept,and the data are converted into electronic statistical tables.SPSS 20.0 is used to carry out statistical analysis,correlation Analysis: For continuous variables,the correlation Coefficient and significance were calculated by correlation analysis.Result1.A total of 39 strains of pathogenic bacteria were isolated from the bacterial cultures of 27 patients in the infected group.17 strains of Escherichia coli,accounting for 43.6%,7 strains of Baumann’s immobile bacteria,accounting for 17.9%,and 5 strains of Staphylococcus acuity,accounting for 12.8%,in addition,Enterobacter Cloacae,Enterococcus,proteus were accounted for less.2.Through the analysis of drug sensitivity,the results showed that the rates of drug resistance of ESBLs-ECO(producing ultra-broad-spectrum beta-lactamase E.coli),ABA(Bowman aureus),SA(Staphylococcus aureus),PAE(copper-green pseudomonas)were different to different drugs,and all of them showed severe multidrug resistance,and the antibiotics with good overall antibacterial effect were inipenem and cefoperazone.ConclusionThe pathogens and drug resistance of patients with Class Ⅱ surgical incision infection in our hospital are different.The infection strains are generally multi-drug resistant strains,mainly ECO.In clinical practice,drug use should be guided by etiology and related drug sensitivity analysis.The results of sensitivity analysis showed that impenem and cefoperazone had low relative drug resistance rate,which could be used early in patients with incisional infection to reduce the risk of adverse consequences. |
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