Effects Of Meal Replace-led Lifestyle Management On Quality Of Life In Patients With Type 2 Diabetes

Objective:Using the SF-36 scale as the measurement tool,this study explored the influence of lifestyle management led by meal replacement diet on the quality of life of patients with type 2 diabetes and analyzed the influencing factors,so as to provide suggestions and countermeasures for improving the quality of life of patients with T2 DM.Methods:A total of 400 patients with type 2 diabetes treated in the Affiliated Hospital of Yan’an University from March 2017 to March 2020 were selected and divided into observation group and control group according to patients’ wishes,with 200 patients in each group.A total of 179 cases were included in the actual observation group and 195 cases in the control group for 42 days.The intervention given to the observation group was lifestyle management dominated by meal replacement diet,including four parts:enhanced meal replacement package,personalized meal list,aerobic exercise,and one-to-one guidance from health consultant.The control group was given a conventional diabetic diet with moderate aerobic exercise.During the intervention,patients in both groups were selected hypoglycemic drugs and adjusted the dose under the guidance of doctors in our department.Comparison of the first two groups of basic data(age,gender,education level,marital status,occupation,monthly income);General information(smoking,alcohol consumption,course of diabetes,history of hypertension,history of hyperlipidemia,history of hyperuricemia);Safety data after conditioning(reduction/withdrawal of hypoglycemic drugs,adverse reactions);Clinical data before and after conditioning(body weight,fasting blood glucose(FPG),glycosylated hemoglobin(HBAC1),triglyceride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C)));SF-36 scale data before and after conditioning(energy(VT),social function(SF),affective function(RE),mental health(MH),physical function(PF),physical function(RP),physical pain(BP),general health(GH),mental health(MCS),physical health(PCS)).SPSS22.0 software was used for statistical processing.Rank-sum test of two independent samples and paired rank sum test were used to compare the difference in quality of life between the two groups.Chi-square test was used to analyze the factors affecting the change of quality of life in the observation group.Results:1.Comparison of quality of life between the observation group and the control group before and after intervention: before intervention,there was no statistical significance in the scores of 8 dimensions and MCS and PCS between the two groups(P > 0.05).After 42 days of intervention,the scores of VT,RE,PF,RP,GH as well as MCS and PCS in the observation group were higher than those in the control group,with statistical significance(P < 0.05).There was no significant difference in SF,MH and BP levels(P > 0.05).After 42 days of intervention,the eight dimensions,MCS and PCS scores of the observation group were all increased,with statistical significance(P < 0.05).In the control group,the scores of VT,SF,MH,PF,GH and MCS and PCS were increased with statistical significance(P < 0.05),while the scores of Re,RP and BP were not changed with statistical significance(P > 0.05).2.Factors affecting the quality of life in the observation group: during the adjustment period,gender,age,alcohol consumption,history of hypertension,reduction/withdrawal of hypoglycemic drugs,adverse reactions,weight loss,improvement of Hb A1 c,improvement of TG and improvement of LDL-C had influences on the improvement of mental health,with statistical significance(P < 0.05).Age,history of hypertension,history of hyperlipidemia,adverse reactions,weight loss,improvement of FPG,TG and LDL-C had significant effects on the improvement of physical health(P< 0.05).Conclusions:1.Lifestyle management led by meal replacement diet and traditional diabetes diet management can both improve the quality of life of patients with type 2 diabetes,and the former has a more significant effect.2.During the conditioning period,mental health improvement was related to gender,age,alcohol consumption,history of hypertension,reduction/withdrawal of hypoglycemic drugs,adverse reactions,weight loss,Hb A1 c improvement,TG improvement,and LDL-C improvement;Physical health improvement was related to age,history of hypertension,history of hyperlipidemia,adverse reactions,weight loss,FPG improvement,TG improvement,and LDL-C improvement.