| Objective To explore the effect of serratus anterior serratus anterior plane block(SAPB)on postoperative analgesia in elderly patients undergoing thoracoscopic radical resection of lung cancer,as well as the effect on patients’ postoperative recovery.Methods From October 2019 to June 2020,60 patients in the First Affiliated Hospital of Bengbu Medical College who were to undergo thoracoscopic radical resection of lung cancer were selected and divided into P group and SP group with 30 cases each by a simple random method.Patients in P group received intravenous patient-controlled analgesia,SP group received continuous SAPB analgesia.The VAS scores of rest and activity,quality of postoperative recovery(Qo R-40)scores,CD4+,CD4+/CD8+,and postoperative adverse events were compared between the two groups before and after 1,3,and 7 days surgery.Results Compared with group P,VAS-R and VAS-A of SP group decreased significantly in d1 and d3,and VAS-A improved more significantly(P<0.05).The QOR-40 score of group SP in d1 and d3 was higher 6.3 than group P(P<0.05).The immunosuppression were significantly lower than that of P group in d1、d3(P<0.05),And there was no difference in immune function of SP group at 7 days after operation and before operation(P>0.05).the rate of nausea and vomiting and hypoxemia was significantly lower than that of group P(P<0.05).Conclusion As a postoperative analgesic strategy,continuous serratus anterior muscle plane block guided by ultrasound can significantly reduce postoperative pain in elderly patients undergoing thoracoscopic radical resection of lung cancer,reduce stress response and immunosuppression,and promote early recovery of patients. |