| Objectives:To investigate the feasibility of diffusion tensor imaging（DTI）in the assessment of cartilage injury of the knee tibiofemoral joints,and to provide basis for the early clinical diagnosis and treatment of knee joint cartilage injuries.Methods:From October 2019 to April 2020,23 patients with tibial femoral cartilage injury were confirmed by arthroscopy after conventional MRI,3D-DESS and DTI sequences were scanned.The FA value and ADC value of damaged cartilage of the tibiofemoral joint were measured by two senior doctors in the images obtained from the DTI sequence.In addition,measure the FA and ADC values of the normal cartilage near the cartilage lesion as controls and calculate the absolute value of FA difference and ADC difference between damaged cartilage and normal cartilage respectively.SPSS 25.0was used for statistical analysis.Results:1 FA values of damaged cartilage of the tibiofemoral joint are lower than those of normal cartilage,whie ADC values are opposite.The differences are statistically different（P<0.05）.2 Correlation analysis between the absolute value of FA difference,ADC difference and the degree of articular cartilage injury:The absolute value of FA difference and ADC difference are positively associated with the degree of articular cartilage injury（r=0.898、0.877,P<0.001）.3 The AUC of the absolute value of the FA difference evaluates is 0.950,and the optimal threshold,sensitivity and specificity are 0.162,89.7%and89.4%,respectively.The AUC of the absolute value of the ADC difference is0.983,and the optimal threshold,sensitivity and specificity are 0.170×10-3mm2/s,93.1%and 93.6%,respectively.Conclusions:DTI technology can quantitatively evaluate the cartilage injury of tibial femoral joint.The absolute value of FA difference and ADC difference between damaged cartilage and normal cartilage can be used as evaluation indexes of cartilage damage,it is important for early clinical diagnosis of knee tibiofemoral joint cartilage damage. |
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