Investigation And Analysis Of Influencing Factors On The Quality Of Life Of Maintenance Hemodialysis Patients

Objective:To investigate the quality of life（QOL）and its influencing factors of mainten-ance hemodialysis（MHD）patients and analyze the related factors affecting QOL scores,in order to provide scientific basis for improving the QOL of MHD patients in the future.Methods:We performed a cross-sectional study which included the MHD patients who visited the blood purification center of Affiliated Hospital of Youjiang Medical University for Nationalities from June 1 to November 30,2020,collected the MHD patient’s demographic characteristics and general information,record clinical information with hemodialysis related materials and medical quality indexes,and used the specific scale kidney disease quality of life short form,version1.3(KDQOL-SF^TM1.3)to conduct a field survey and assess the MHD patients’quality of life.Results:（1）A total of 217 cases of MHD patients were included in this statistical analysis.Among them,there were 150 male（69.10%）and 67 female（30.80%）,with a male to female ratio of about 2.24:1.The average age was 49.80±14.17 years old.The majority proportion were twice and three-times weekly hemodialysis（81.11%）,while the proportion of two-times weekly hemodialysis was the highest（66.82%）.The average period of hemodialysis was 30.19±28.79months.The primary diseases were mainly chronic glomerulonephritis,diabetic kidney disease and hypertensive nephropathy.（2）The medical quality indicators of MHD patients in this study were as follows:The average of systolic blood pressure（SBP）was153.52±21.32mm Hg,serum albumin（Alb）was 39.81±5.46g/L,hemoglobin（Hb）was101.57±21.91g/L,serum calcium（Ca）was 2.20±0.24mmol/L.The average serum phosphorus（P）was 3.16mmol/L,the median was 1.97mmol/L,and the interquaternary interval was 1.06mmol/L.The average parathyroid hormone（PTH）was 467ng/L,the median was 340.20ng/L,and the interquaternary interval was 517.25ng/L.The standard-reaching rate of medical quality indicators was generally low,the SBP,Alb,Hb,Ca,P and PTH in MHD patients was 64.06%,82.95%,46.54%,64.43%,29.03%and 18.89%respectively.（3）QOL of MHD patients in our center:The overall score of 36-item short form health survey（SF-36）was48.33±10.67,of which the physical component summary（PCS）was 49.61±12.39 and the mental component summary（MCS）was 47.05±10.53.The comprehensive score of kidney disease targets areas（KDTA）was 57.65±8.68.（4）We found that gender,age,education level,employment status,way of living,family economic level,primary disease,hemodialysis mode,vascular access,frequency of dialysis,period of hemodialysis,and the level of SBP,Alb,Hb,CRP,Ca,P,PTH were independent correlation factors affecting the QOL score of MHD patients.Conclusion:（1）The quality of life of MHD patients in our center is still relatively low.（2）This survey shows that general socio demographic factors:such as gender,age,education level,employment status,way of living,family economic level;hemodialysis related factors:such as primary disease,hemodialysis mode,vascular access,frequency of dialysis,period of hemodialysis;medical quality indicator factors:such as SBP,Alb,Hb,CRP,Ca,P and PTH can affect the quality of life of MHD patients to a certain extent.（3）The rate of meeting medical quality indicators for MHD patients in our center still needs to be improved,especially Hb,P and PTH.