Analysis Of Related Risk Factors Of Different Pathological Types Of Gastric Polyps In Western Guangxi

Objective: The emphasis of this study is to learn and analyze the clinical characteristics of patients with gastric polyps and the related risk factors of different pathological types of gastric polyps,and to improve the understanding and diagnosis of gastric polyps.Besides,this paper discuss better ways of early detection,early treatment and early prevention to provide theoretical reference for the treatment of clinical patients with gastric polyps.Methods:(1)The clinical data of 274 patients with Gastric polyps diagnosed by electronic gastroscopy and pathological examination in the Affiliated Hospital of Youjiang Medical University for Nationalities from January 1,2017 to June 30,2020 were retrospectively analyzed.According to different pathological types,they were divided into the groups of adenomatous polyps(APS),fundic gland polyps(FGP),hyperplastic polyps(HPS hyperplastic polyps)and inflammatory polyps(IP);(2)The risk factors included: general information(gender,age,nationality,place of birth,occupation,BMI,smoking history,drinking history,marital status),laboratory test indexes(PGI,PGII,13 carbon urea expiratory test,Serum Helicobacter pylori antibody,G-17),location and number of gastric polyps,accompanying diseases and pathological types;(3)In data analysis: single-factor analysis was adopted in the case of multiple factors that affect different pathological types of gastric polyps.And then logistic regression analysis of multiple factors was done if any statistical differences existed.As a Result,there was statistically significance as the difference of P<0.05.Results:(1)The data of totally 274 patients with gastric polyps were collected,The ratio of male to female was 1:2.91 from the age of 21 to 86(with an average of 51.7±10.88 yeas old),most of them are Zhuang nationality.The infection rate of Helicobacter pylori was83.94%.(2)Clinical manifestations presented abdominal pain(77.74%),abdominal distension(42.34%),acid reflux(17.15%),nausea and vomiting(15.33%)and belching(12.41%).(3)In this study,patients with fundus gland polyps were the most common,mainly located in the fundus and body of stomach;hyperplastic polyps and inflammatory polyps were mainly located in the body and antrum of stomach.(4)Univariate analysis results showed that there were statistically significant differences(P<0.05)in fundic gland polyps,gastric hyperplastic polyps,inflammatory polyps,including the ones withsmoking history(P=0.031)and drinking history(P=0.006),HP infection(P=0.012),PGI(P=0.017),PGII(P=0.035),PGR(P<0.001),G-17(P=0.012),location of gastric polyps(P<0.001),and so on.There were no significant differences in gender(P=0.864),nationality(P=0.356),age(P=0.580),occupation(P=0.729),marital status(P=0.426),BMI(P=0.524),accompanying diseases(P>0.05)and the number of polyps(P=0.781).(5)Logistic regression analysis was applied in exploring the single factors we discussed above,which indicated that:(1)For the disease of fundic gland polyps,there were statistical significance in drinking history(P=0.028,OR=3.901,95% CI:1.163 to 13.09),and the differences of PGI(P=0.02,OR=0.414,95%CI:0.197 to 0.870)and PGII(P=0.006,OR=0.200,95%CI:0.064 to 0.631);(2)The same as difference of PGII(P=0.021,OR=0.198,95%CI:0.050 to 0.786)for gastric hyperplastic polyps.Conclusion: This study found that the risks like smoking history,drinking history,HP infection,PGI,PGII and G-17 cause different pathological types of gastric polyps;Drinking history was an independent risk factor for patients with gastric fundus polyps,PGI and PGII were protective factors for patients with gastric fundus polyps,and PGII was protective factor for patients with proliferative polyps.