Analysis Of Virus Spctrum In Hospitalized Children With Acute Respiratory Infection

Objective:To analyze the characteristics of virus spectrum in the Korean nationality and Han children with acute respiratory tract infection in our hospital,and provide reference for prevention and treatment of acute respiratory tract virus infection in children in Yanbian area.Methods:From December 2017 to November 2018,986 caese of the Korean nationality and Han children who were treated for ARTI in Affiliated hospital of YanBian university,were enrolled in the present survey,and record The results and epidemiological information of five respiratory viruses in serum of 986 children detected by elisa in our hospital.In addition,the five respiratory viruses include RSV,ADV IFVA,IFVB and PIV.Result:1.Virus detection rate:Among the 986 children with acute respiratory tract infection,the total positive virus detection rate was 20.6%,and the single virus detection rate was 19%.The highest rate of the five viruses was IFVB(12.4%),followed by IFVA(2.9%).2.The distribution of virus in the two ethnic groups:The total virus detection rates of the Korean nationality and Han children were 8.2%and 12.4%.There was no statistic difference in detection rate of the Korean nationality and Han children in total viruses and different viruses(all P>0.05).3.The distribution of viruses in different genders:The detection rate of virus was 11.3%in boys and 9.3%in girls,There was no statistical difference in the detection rate of total virus and each virus in different genders(all P>0.05).4.The distribution of the virus at different ages:the<3 year old group had the highest virus detection rate,followed by the 3-6 year old group and the 6-14 year old group(9.0%,8.3%,3.2%).There was no statistical difference in the distribution of total virus and each virus in the three age groups(all P>0.05).The highest virus detection rate of the Korean nationality children was in the group aged 3-6 years(3.7%),while the highest rate of Han children was in the group aged<3 years(6.2%).However,there was no statistical difference in the virus detection rate of children of the two ethnic groups in the three age groups(P>0.05).5.The virus distribution in different seasons:the highest virus detection rate of four seasons was winter,followed by spring(7.5%and 6.3%).There was a statistical difference in virus detection rate among the four seasons(P<0.05),in which RSV had the highest detection rate in spring and IFVA had the highest detection rate in winter(all P<0.05).The seasons with the highest virus detection rate were winter and spring(4.7%and 4.5%).The virus detection rate of Han children in spring and autumn was higher than that.of the Korean nationality children,and lower than that of the Korean nationality children in winter(P<0.05).The seasonal distribution of virus detection rate of children in the two ethnic groups was statistically different(P<0.05).6.The clinical manifestations and diagnosis:The diagnosis of virus positive children was mainly acute upper respiratory tract infection,with a composition ratio of 40.9%and the clinical symptoms were mainly fever and cough,with a composition ratio of 87.7%and 60.6%.Conclusion:1.From 2017 to 2018,Influenza B virus is the major pathogen of ARTI hospitalized children in our hospital.The main popular seasons of virus are winter and spring.Infants and young children are the main population affected by virus.2.Han children are vulnerable to virus than the Korean vulnerable children,in spring and autumn,however,Ethnic Korean children are more susceptible to virus in winter.