To Evaluate The Efficacy And Safety Of Laparoscopic Approach In The Treatment Of Early Cervical Cancer

Compared the meta-analysis of minimally invasive surgery and open surgery for early cervical cancerObjective: To evaluate the efficacy and safety of minimally invasive surgery and open surgery in the treatment of early cervical cancer.Methods: Used computer to retrieval Cochrane,MEDLINE,EMBASE,SCIENCE-DIRECT,PUBMED,CNKI,Wan Fang,VIP database,retrieval time from building to January 2020,and recover into literature references.Found the contrast of minimally invasive surgery and open surgery for the treatment of early cervical cancer randomised controlled trials and clinical controlled trials,with Revman5.3 software for Meta analysis.Results: A total of 2061 patients were included in 6 non-randomized controlled clinical trials,including 1129 patients in the experimental group(minimally invasive surgery group)and 932 patients in the control group(open surgery group).Meta analysis results show that compared with open surgery group,minimally invasive surgical operation time and laparotomy group had no significant difference(P = 0.09),but the intraoperative blood loss,intraoperative complications and postoperative complications,the incidence of intraoperative blood transfusion were superior to laparotomy group(P < 0.05),but lower overall survival of minimally invasive surgery group(P = 0.005),the total 5years recurrence rates have no obvious difference(P = 0.70).Conclusions: Existing studies show that minimally invasive surgery causes less damage to patients than open surgery,but the overall survival rate is worse than open surgery.Efficacy and safety of laparoscopic radical resection of cervical cancer in the treatment of early cervical cancer Objective: To compare the efficacy and safety of laparoscopic and open radical hysterectomy in the treatment of early cervical cancer and the influencing factors of laparoscopic surgery in the treatment of early cervical cancer recurrence.Methods: Retrospected analysis from January 1,2000 to 2016 on August31,hospitalized in hospital,who was the FIGO stage in Ⅰ A1-Ⅱ A2 in cervical cancer patients with clinical data,according to the different ways of operation,is divided into 320 cases of laparoscopic surgery and open surgery group 91 examples.To compare of two groups of patients with operation time,intraoperative blood loss,intraoperative injury,postoperative complications,postoperative anal exhaust time,pull the urine tube time,postoperative recurrence rate.And using Logistic regression to laparoscopic surgery group recurrence of multi-factor analysis.Results: Compared with the open operation group,the operation time of the laparoscopic operation group was shorter,and the comparison between the two was statistically significant(P < 0.05).The amount of blood loss,postoperative catheter extraction time and anus exhaust time of the laparoscopic operation group were all better than that of the open operation group,with statistical significance(P < 0.05).On the premise that there was no significant difference between the two groups in lymphatic vascular space infiltration,tumor diameter,muscle layer infiltration depth,parastatal infiltration,vaginal incision margin,and lymph node metastasis(P > 0.05),there was no significant difference in1-year,3-year,5-year recurrence rate and tumor-free survival rate(P >0.05).Single factor and multiple factors analysis suggests a positive lymph node metastasis,tumor diameter 2 cm or more,FIGO staging > ⅠB1 stage,pathological types for non squamous carcinoma is a risk factor for recurrence of laparoscopic surgery group.Conclusion: Laparoscopic surgery for early cervical cancer can reduce intraoperative and postoperative complications.And lymph node metastasis,tumor diameter 2 cm or more,FIGO staging > Ⅰ B1 stage,pathological types for non squamous carcinoma is a risk factor for recurrence of laparoscopic surgery group.