| ObjectiveTo explore the clinical effect of conventional exercise(aerobic exercise combined with resistant exercise)、7 minutes HICT(High-Intensity-Circuit-Training)treat on the plegm type of women with Polycystic Ovary Syndrome and insulin resistance(PCOS-IR),in order to provide clinical proof and reference program for erercise intervention to be pupularzied in clinic.MethodsThis study was a randomized controlled clinical research,69 PCOS-IR women with plegm type of randomly were divided into 3 groups:conventional exercise(aerobic exercise combined resistance exercise)group,7 minutes HICT group and control group that was treated with Metformin.Each group got their intervention for 12 weeks respectively.Before and after the intervention,we measured fast blood sugar and 2 hour post-meal blood sugar,fast insulin and 2 hour post-meal insulin and insulin resistance index(HOMA IR),waistline,waist hip rate(WHR),body mass index(BMI),body fat rate,blood lipids(including TG,TC,LDL-C and HDL-C),reproductive hormones(including FSH,LH,LH/FSH and T),BBT,TCM syndrome grade,survival quality and so on.Result1.After intervention,the 3 groups all had lower HOMA-IR,the difference was statistically significant(P<0.05).There was no significant difference among the 3 groups in this part(P>0.05).The conventional exercise ones had lower fast insulin and 2 hour post-meal insulin,the 7 minutes HICT ones had lower fast insulin,while the control ones had lower fast blood sugar and 2 hour post-meal blood sugar.2.After intervention,the 3 groups all had lower body fat rate.And conventional exercise group and control group had lower body weight and BMI,conventional exercise group and 7 minutes HICT group had lower WHR,the difference was statistically significant(P<0.05).3.After intervention,conventional exercise group and 7 minutes HICT group had lower TG、TC、LDL-C(P<0.05).Conventional exercise group had higher HDL-C(P<0.05),control group had lower TG(P<0.05).4.After intervention,LH、LH/FSH decreased significantly in conventional exercise group and 7 minutes HICT group(P<0.05),while there was not significant difference between the two groups(P>0.05).T decreased significantly in control group(P<0.05).5.After intervention,TCM syndrome grade decreased significantly in 3 groups(P<0.05).There was no significant difference among the 3 groups in this part(P>0.05).6.After intervention,survival quality were improved in conventional exercise group and 7 minutes HICT group(P<0.05),and both of them had a higher score than the control ones in the emotional dimension.Conclus ionThis clinical study show that conventional exercise and 7 minutes HICT have therapeutic effect on improving the insulin sensitivity in the plegm type of women with Polycystic Ovary Syndrome and insulin resistance(PCOS-IR)as Metformin does.Metformin can significiantly reduce the level of fast blood sugar and 2 hour post-meal blood sugar,conventional exercise can significiantly reduce the level of fast insulin and 2 hour post-meal insulin,and 7 minutes HICT can significiantly reduce the level of fast insulin.All three have lower body fat rate,conventional exercise and Metformin can significiantly reduce the level of body weight,BMI,Metformin can significiantly reduce TG and T after invention.Conventional exercise and 7 minutes HICT can significiantly reduce the level of WHR,LH,LH/FSH and LDL-C,conventional exercise can increase patients’ HDL-C.What’s more,all of them also can dramatically improve the syndrome of phlegm-dampness,and exercise not help to release patients’emotional breakdowns but also improves their mental state.It is recommended that PCOS-IR patients with poor mood such as anxiety can choose exercise to improve their state.If PCOS-IR patients that bneed to lose weight or with higher fast insulin and 2 hour post-meal insulin,or lower HDL-C can choose conventional(aerobic exercise and resistance exercise).If they do not need to lose weight or only with higher fast insulin,can choose HICT. |