The Influence Of Fitness Qigong Baduanjin On Emotion,Cellular Immune And Quality Of Life Of Postoperative Patients With Colorectal Cancer

PurposeIn most cases,postoperative patients with colorectal cancer have problems of negative emotions,decreased immunity and poor quality of life.This study explored the curative effect of Fitness Qigong Baduanjin on cellular immune function,quality of life and negative emotions of postoperative patients with colorectal cancer,and analyzed the relationship between cellular immune status and anxiety,depression of postoperative patients with colorectal cancer,so as to provide theoretical reference for clinical rehabilitation.MethodsSixty postoperative patients with colorectal cancer aged 45-65 were recruited from Liaoning Cancer Hospital,and the intervention was carring out from March to October 2019.Experimental group（27 patients）and control group（28 patients）were randomly divided by random number table method,and a total of 24 weeks（four days a week,two times a day and 45-60 minutes per time）of Fitness Qigong Baduanjin were finished in experimental group;while control group who maintained the original level of physical activity.During intervention,T-lymphocyte subsets immune cell,mood and quality of life test were carried out on the baseline,12^thand 24^thweek;simultaneously,sorting and statistical data were collected and sorted to analyze the effects of Fitness Qigong Baduanjin on cellular immune index,negative mood and quality of life of postoperative patients with colorectal cancer.Results1.Compared with the baseline,the anxiety and depression scores of the experimental group decreased significantly（P<0.01）after 12 weeks exercise intervention,however,no significant difference were found in the control group（P>0.05）.Compared with the control group,significant difference was found in anxiety score（P<0.05）,depression score（P<0.01）in the experimental group after 12weeks of exercise intervention;the anxiety and depression scores of the experimental group decreased significantly（P<0.01）after 24 weeks exercise intervention.2.Compared with the baseline,no significant difference was found among the subjects in the experimental group except for the change of CD8⁺%（P>0.05）after12 weeks exercise intervention,and the other T-lymphocyte subsets were found significantly higher（P<0.01）,however,no significant difference were found in the scores of the control group（P>0.05）.Compared with the control group,after 12weeks of exercise intervention,CD3⁺%,CD4⁺/CD8⁺in the experimental group showed significant difference（P<0.01）,and CD4+%also showed significant difference（P<0.05）;on the 24^th week during exercise intervention,significant differences in CD3⁺%,CD4⁺%,CD4⁺/CD8⁺,NK⁺%were found in the experimental group（P<0.01）.3.Compared with baseline,after 12 weeks of exercise intervention,the total scores of life quality and emotional status of the subjects in the experimental group increased with extremely significant difference（P<0.01）.Meanwhile,the physiological status and additional attention scores increased with significant difference（P<0.05）;compared with baseline,after 24 weeks of intervention,the total scores of quality of life and all dimensions in the experimental group increased with significant difference（P<0.01）while no significant difference were found of the scores in the control group（P>0.05）.Compared with the control group,after 12 weeks of exercise intervention,the functional status of the test group showed extremely significant difference（P<0.01）,and the social/family status,emotional status,total score of quality of life,physiological status score and additional attention score of the experimental group increased,showing significant difference（P<0.05）;after 24weeks of exercise intervention,the total score of quality of life and all dimensions in the experimental group increased with significant difference（P<0.01）.4.After exercise intervention,CD3⁺%of subjects in the experimental group was negatively correlated with HAMD and HAMD scores（r₁=-0.406,P<0.05;r₂=-0.410,P<0.05）;CD4+%of subjects in the experimental group was negatively correlated with HAMA score（r=-0.479,P<0.05）.Meanwhile,CD3+%and HAMD,HAMD scores of subjects in the experimental group were analyzed by multiple linear regression,and the final fitting equation was Y=-0.205x₁-0.238x₂（P<0.05）;after exercise intervention,the CD4⁺%and HAMD scores of the subjects in the experimental group were analyzed by linear regression analysis,and the final fitting equation was Y=-0.175X₁+1.856（P<0.05）.Conclusion1.Postoperative patients with colorectal cancer are generally accompanied with anxiety,depression and other emotional disorders,the cellular immune function is declined,which affects the quality of life of patients.2.Fitness Qigong Baduanjin can relieve the anxiety,depression and the cellular immune function of postoperative patients with colorectal cancer,and then better the quality of life.3.There is a negative correlation between scores of anxiety,depression and some cellular immune indexes in postoperative patients with colorectal cancer;which means the more serious anxiety and depression disorders are,the worse their immune function might be.