Clinical Study On Influencing Factors And Complications Of Critical Illness In Preterm Infants

Objective To explore the factors affecting critical premature infants and complications during hospitalization and to reduce the occurrence of critical premature infants and complications during hospitalization by comparing the maternal pregnancy situations,general situations,transport modes and complications during hospitalization of premature infants admitted to hospital.Methods 922 premature infants from the province and surrounding areas were divided into critical preterm infants group(316 cases)and non-critical preterm infants group(606cases)according to Critical illness score.The general situations and maternal pregnancy situations,transport modes,complications of premature infants were retrospectively analyzed between critical and non-critical preterm infants.Results 1.Comparing the general situations of critical and non-critical premature infants :admission time after birth,birth weight,gestational age,modes of delivery,1-minute and 5-minute Apgar scores,hospitalization stays,the differences were statistically significant(p<0.05)in critically ill and non-critically ill groups of preterm infants in comparison;the gender,fetal times,birth times,fetal distress were compared in the two groups of premature infants,the differences were not statistically significant(p>0.05).2.Comparing the maternal pregnancy situations of critical and non-critical premature infants: the composition ratios of placenta previa and test-tube baby in critically ill preterm infants were higher than those of non-critical group and the incidence of premature rupture of membranes was lower than that of non-critically ill preterm infants,the differences were statistically significant(p<0.05).The premature infants in the two groups had amniotic fluid situation,vaginal bleeding,placental abruption,twins,infection,preeclampsia,pregnancy with diabetes,anemia,thyroid dysfunction,cholestasis syndrome,viral hepatitis,abortion history,mother’s age and occupation,the differences were not statistically significant(p>0.05).3.Comparising the transport methods of critical and non-critical premature infants: 689 preterm infants were admitted to hospital by extrauterine transport(356 by the professional transport;333 by the non-professional transport),and 233 preterm infants were admitted by maternal transport.52.2% of critically ill premature infants were admitted to hospital through professional transport,25.9% of critically ill preterm infants were admitted through non-professional transport,21.8% of critically ill preterm infants were admitted through maternal transport.The proportion of critically illness preterm infants with professional transport was higher than that of non-professional transport and maternal transport of preterm infants(p<0.05).4.Logistic regression analysis of influencing factors in 316 critically ill preterm infants showed that the protective factors of premature infants were heavy of birth weight and high of5-minute Apgar score;risk factors were cesarean section and late of admission time after birth.5.Comparing complications of critical and non-critical premature infants during hospitalization: the proportions of anemia,infection,NRDS,electrolyte,acid-base balance disorders,respiratory failure,hypoproteinemia,asphyxia,sepsis,scleredema,bronchopulmonary dysplasia,pulmonary hemorrhage,hyperglycemia and pneumothorax in critically ill premature infants were higher than those of non-critical preterm infants,the differences were statistically significant(p<0.05).There were no significant differences in intracranial hemorrhage,necrotizing enterocolitis,gastrointestinal hemorrhage and retinopathy between critically ill and non-critical preterm infants(p>0.05).Conclusions 1.Factors affecting the occurrence of critical illness in premature infants are: gestational age less than 34 weeks,low of birth weight,caesarean section delivered,low of 1 minute and 5 minutes Apgar score and late admission time.2.The factors affecting the occurrence of critical illness in premature infants are: test tube babys and maternal placenta previa.3.Premature infants with critical illness are mainly admitted to hospital through professional transport.4.Common complications of critically ill premature infants during the hospitalization include anemia,infection,respiratory distress syndrome,electrolytes and acid-base balance disorders.et al.