| Objective:To investigate the clinical effect of concentrate growth factor(CGF)on distal molar bone defects of second molar in mandibular impacted wisdom teeth.Methods:Methods:In this study,a total of 70 patients who attended the Oral Surgery Clinic of the First Affiliated Hospital of Xinjiang Medical University from September 2019 to March 2020 were collected and randomly divided into an experimental group and a control group,with 35 cases in each group.Experimental group:CGF was inserted into the bone defect of adjacent second molars and tooth extraction after extraction of impacted mandibular wisdom teeth;Control group:CGF was sutured directly after the extraction of mandibular impacted wisdom teeth.The comparison parameters were:the pain,swelling degree and mouth opening degree were compared on the 1st,3rd and 7th days after operation;the healing index on the 3rd and 7th days after operation;probing depth(PD)of the distal gingival margin of the second molar immediately and 6 months after operation;bone gain(BG)of the two groups were examined by CBCT at 6 months after operation.Results:the degree of pain in the experimental group was significantly lower than that in the control group on the 1st and 3rd days after operation(P<0.05),but there was no significant difference between the two groups on the 7th day after operation(P>0.05).There was no significant difference in the degree of facial swelling and mouth opening between the two groups(P>0.05).The healing index(the smaller the better)of the experimental group was lower than that of the control group on the 3rd and 7th days after operation,and the difference was statistically significant(P<0.05).The PD value of the experimental group was significantly higher than that of the control group from immediately to 6 months after operation(P<0.05).Conclusion:CGF can effectively relieve pain and promote the healing of soft and hard tissues in the distal part of the second molar after tooth extraction. |
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