The Medication Characteristics Of Associate Professor Zhang Lixiu In The Treatment Of Stable COPD Based On Data Analysis

Objective: By collecting and sorting out the outpatient cases of tutor in the treatment of stable chronic obstructive pulmonary disease(COPD),analyze and summarize the medication characteristics of tutor in the treatment of stable COPD by means of data statistics.Methods: The data were collected and sorted out,the database was established,the syndrome types,drugs and the nature,taste and meridian of high-frequency drugs were counted,and the high-frequency drugs were systematically clustered.Finally,the medication characteristics of tutor in the treatment of stable COPD were analyzed and summarized.Results: In this study,the stable stage of COPD(1)syndrome type: can be divided into middle energizer deficiency cold,phlegm retention syndrome;lung spleen qi deficiency syndrome;kidney yang deficiency,cold retention syndrome;lung kidney qi deficiency syndrome;lung kidney yin deficiency syndrome.(2)Drug classification: tonifying deficiency drugs,relieving exterior drugs,resolving phlegm,relieving cough and asthma drugs,promoting blood circulation and removing blood stasis drugs and warming interior drugs are the most common drugs.(3)Drug frequency: a total of 113 kinds of traditional Chinese medicine were used,of which the proportion of high-frequency drugs was 70.28%.(4)High frequency drug properties: warm drugs accounted for the largest proportion.(5)Most of the high-frequency drugs are sweet,pungent and bitter.(6)High frequency drugs mainly belong to lung,spleen and kidney meridians.(7)Four cluster formula groups: the first group: jujube,Cimicifuga,bupleurum,ginger,angelica,astragalus,Pericarpium Citri Reticulatae,Atractylodes macrocephala,ginseng,Rhizoma Pinelliae,Radix Paeoniae Alba;the second group: Ramulus Cinnamomi,radix paeoniae rubra,peach kernel;the third group:yam,Cornus officinalis,Alisma orientalis,cortex Moutan,radix rehmanniae,cinnamon,Fructus Wuweizi,Poria;the fourth group: Magnolia officinalis,amethyst,dried ginger,prepared aconite,asarum,fried licorice.Conclusion: combined with data analysis and clinical follow-up study,the medication characteristics of tutor in the treatment of stable COPD are summarized as follows:(1)Pay attention to the use of warm medicineThe four Qi analysis of high-frequency drugs shows that warm drugs are often used to warm the lung,spleen and kidney,warm the cold phlegm,warm the meridians,and warm the Qi.(2)Sweet,spicy and bitterIn the statistical analysis of five high-frequency drugs,sweet drugs are often used to tonify,pungent drugs to block Qi and blood;bitter drugs can prevent excessive tonic,and dry dampness to resolve phlegm.In addition,the combination of xinkaikujiang is often used to dredge Qi and eliminate phlegm and blood stasis.(3)The treatment was mainly based on lung,spleen and kidneyIn the analysis of channel tropism of high-frequency drugs,the treatment of COPD in stable stage is mainly based on five zang organs,especially the adjustment of lung,spleen and kidney.(4)Consolidate the sourceAccording to the statistical analysis of drugs,it can be found that the combination of tonifying deficiency and warming interior can play the role of warming and tonifying together,so as to strengthen the body and strengthen the foundation;the combination of phlegm resolving,cough relieving and asthma relieving drugs,blood activating and stasis removing drugs can also be used to eliminate the pathogenic factors of phlegm and blood stasis.Cluster analysis of high-frequency drugs showed that the first cluster group was mainly used for tonifying lung and spleen;the third cluster group was mainly used for tonifying kidney essence;the fourth cluster group was mainly used for warming yang and reducing adverse reactions;the second cluster group was mainly used for clinical compatibility to promote blood circulation and remove blood stasis.Combined with the analysis of the nature,taste and meridian tropism of high-frequency drugs,it can be seen that the main functions of drugs in the stable phase of COPD are as follows: first,it is mainly used to tonify the deficiency of lung,spleen and kidney,so as to strengthen the body and strengthen the foundation;second,it is used to remove phlegm and blood stasis,so as to eliminate the pathogenic factors of phlegm and blood stasis.They work together to reduce the clinical symptoms,reduce and control the number of acute exacerbations,reduce the risk of disease deterioration,prevent disease progression and improve the quality of life of patients.