Clinical Study On The Treatment Of Deficiency Syndrome Of Spleen And Kidney Yang In Patients With Tremor And Dementia With Modified Huanshaodan

Objective:To observe the clinical efficacy of Huan Shao Dan Jiawei in treating mild cognitive impairment after Parkinson’s disease,and to compare its efficacy and side effects with the control drug donepezil.Methods:Patients with mild cognitive impairment after Parkinson’s disease were selected as the research objects.All patients were determined according to the diagnostic criteria.A total of 134 cases were collected,including 67 cases in the control group and 67 cases in the test group.All patients were treated with anti-Parkinson drugs.The treatment group was treated with Huan Shao Dan Jiawei Decoction,2 days/dose,60 ml/time,3 times/day,warmed for half an hour to 1 hour after meals,and the course of treatment was 3 months.In the control group,the oral drug donepezil hydrochloride was administered once at night before going to bed,starting at 5 mg daily for 2 weeks,and then increasing to 10 mg once a day for 3 months.Monitor the patient’s vital signs,and perform blood routine,blood biochemistry and other related examinations as the patient’s safety indicators.At the same time,a variety of indicators are used to evaluate the efficacy,such as the TCM Syndrome Grading Scale,the MMSE Scale,the MoCA Scale,and other comprehensive evaluations.The effect of Dan addition and subtraction on the treatment of mild cognitive impairment after Parkinson’s disease will be evaluated.Statistical data is introduced into SPSS 22.0 software for analysis.Results:Judging from the scores of the TCM Syndrome Grading Scale,one month after the treatment,the two groups had a decline compared with before the treatment,while the MMSE and MoCA scores increased,and the comparison of the scores of the two groups after treatment was significantly improved(P<0.05);Three months after treatment,both groups were given TCM syndrome classification,MMSE and MoCA scores.Comparing the results of the two groups,the decrease in the treatment group was more significant(P<0.05).From the perspective of the efficacy of TCM syndromes,after 3 months of taking the medicine,there is a significant difference between the two groups,and the treatment group has more advantages(P<0.05).Conclusion:①For patients with Parkinson’s disease and cognitive impairment,the application of Huan Shao Dan Jiawei therapy can achieve better curative effect,and the patient’s cognitive level has improved;②The experimental group has more advantages than the control group,from various scores The results have confirmed this point.There is a difference between the two groups one month after treatment,and the addition of Shao Dan can effectively improve the cognitive impairment of such patients.