Research Of The Influence Of Birthweight Discordant Twins On The Mother And Newborn

Objective:To compare the maternal and neonatal correlation between twins with inconsistent birth weight and twins with the same birth weight,and to explore the relationship between inconsistent twins and maternal diseases during pregnancy and neonatal perinatal diseases.and its effects on the physical growth and neuropsychological development of newborns.Methods:According to the inclusion and exclusion criteria,fifty four pairs of twins born in our hospital from 2018 to 2019 were selected and divided into consistent birth weight group(consistent group)and inconsistent birth weight group(inconsistent group)according to whether the difference in birth weight greater than or equal to twenty percent.The inconsistent group was divided into higher weight group(higher group)and lower weight group(lower group).The basic data of mothers and twins,NICU disease during pregnancy and twins admitted to neonatal intensive care unit,physical growth and development indexes and child neuropsychological development scale scores of all twins were collected.SPSS 26.0 statistical software was used for data processing and statistical analysis,P < 0.05,the difference was statistically significant.Result:1.The proportion of twins with inconsistent birth weights among live births in our hospital from 2018 to 2019 is twelve percent.2.The cesarean section rate and prenatal glucocorticoid use rate in the consistent group were higher than that in the inconsistent group,and the difference is statistically significant(P<0.05);the incidence of placental abnormalities in the inconsistent group was higher than that in the consistent group,and the difference was statistically significant(P <0.05);the consistent group’s Apgar scores at one minute,five minutes,and ten minutes compared with the discordant group,the difference was statistically significant(P<0.05);the incidence of premature rupture of membranes in the consistent group was higher than that of the discordant group,and the difference was statistically significant(P< 0.05);the incidence of hypertension,preeclampsia(PE)and gestational diabetes(GDM)in the inconsistent group was higher than that in the consistent group,and the difference was statistically significant(P<0.05).3.Diseases during admission to NICU: neonatal asphyxia,bronchopulmonary dysplasia,neonatal respiratory distress syndrome,respiratory failure,neonatal pneumonia,neonatal wet lung,intracranial hemorrhage,pathological jaundice,neonatal sepsis,anemia,the incidence of hypoglycemia,cholestasis syndrome,neonatal necrotizing enterocolitis,and retinopathy was not statistically different between the consistent group and the discordant group(P>0.05);the higher group and the lower group In comparison,the difference was not statistically significant(P>0.05).4.At birth,3,6,9 and 12 months of age(corrected month age),there was no statistically significant difference in weight,body length,and head circumference between the consistent group and the discordant group(P>0.05).The average weight of the higher group was higher than that of the lower group at birth,and the average weight,length and head circumference of the higher group were higher than the lower group at 3,6,9,and 12 months of age,and the difference was statistically significant(P<0.05).5.The average weight,length,and head circumference of all twins in this study were lower than the average of male and female children in nine cities in China in 2015;the average weight and length of the same group after 6 months of age exceeded the average weight and length of the nine cities.The average head circumference after 9months of age exceeds the average head circumference of the nine cities;in the discordant group,the average weight,length,and head circumference of the higher group exceed the average of the nine cities after 3 months of age;the average weight,length,and head circumference of the lower group are up to 12 The monthly age has not exceeded the average level of the nine cities,but the gap is smaller than that at birth.6.Multi-factor Logistic regression analysis showed that maternal hypertension and placental abnormalities are independent risk factors for inconsistent twins.7.At the age of 18 months(corrected month age),the test score of the children’s neuropsychological development scale(pediatric heart scale)was lower in the discordant group than in the consistent group,and the difference between the two groups was statistically significant(P<0.05).Conclusion:1.Maternal hypertension and placental abnormality during pregnancy are independent risk factors for twins with inconsistent birth weight.2.The difference in birth weight of twins may have a lasting impact on their long-term growth and development,and the growth and development of twins with inconsistent birth weight should be monitored regularly to improve follow-up compliance.