Analysis Of Clinical Data Of 126 Patients With Eclampsia

Objective:By analyzing the general data,laboratory examination,clinical symptoms,head imaging,and neonatal outcome of early-onset eclampsia and late-onset eclampsia,pre-eclampsia and post-natal eclampsia,in order to draw differences to guide clinical screening prevention and treatment management.Method:Retrospective analysis of the clinical data of 126 patients with eclampsia who were hospitalized and delivered in the obstetrics department of the Second Hospital of Jilin University from January 2008 to October 2020.According to the gestational week at the time of hyperspasmia: the group of <34 weeks is early onset eclampsia(59 cases)and ≥34 weeks are late-onset eclampsia(67 cases),which are represented by group A and group B respectively;each group is divided into prenatal eclampsia group and postpartum eclampsia group according to the time of hyperspasmia.The pre-eclampsia group and post-eclampsia group in the group A are represented by group A1 and A2 respectively;the pre-eclampsia group and post-eclampsia group in group B are represented by group B1 and group B2,respectively.The general data,clinical manifestations,laboratory test indicators and neonatal outcomes of pregnant women were compared.Result:1 :Comparison between group A and group B:The proportion of patients with seizures ≥ 2 times in group A(47%)was significantly higher than that in group B(29.8%)(P<0.05);the prothrombin time in group B was higher than that in group A(P<0.05);Uric acid was significantly lower than that of group A(P<0.05);indirect bilirubin and total bilirubin of group B were higher than those of group A,and direct bilirubin was lower than group A(P<0.05);weight of newborns in group B and newborns Apgar scores at 1 minute and 5 minutes after birth were higher than those of group A(P<0.05);the proportion of patients with urine protein(≥3+)in group A was 82.5%,which was significantly higher than 65%in group B,but the difference between group A and B was not statistically significant(P≥0.05).2 : Comparison between group A1 and group A2:The percentage of neutrophils,direct bilirubin,indirect bilirubin,and total bilirubin in group A1 were higher than those in group A2,and the difference was statistically significant(P<0.05);3 : Comparison between group B1 and group B2:The proportion of headache and visual disturbance in group B1 was significantly higher than that of group B2(P<0.05);the neutrophils in group B2 were significantly higher than that in group B1(P<0.05);Urine protein was statistically significant between the two groups(P<0.05);(4): The head imaging abnormalities of patients with eclampsia mainly showed white matter edema(75.8%)and cerebral infarction(21.6%);patients with white matter edema showed bilateral and/or occipital lobes the most(71.4%).Visual disturbance(39.3%)was the most common subjective symptom;bilateral and/or parieto-occipital lobe and basal ganglia were the most common symptom of cerebral infarction(75%),and the most common subjective symptom was headache(62.5%).Conclusion:1.Patients with early-onset eclampsia have a higher proportion of convulsions(≥2 times)than those with late-onset eclampsia.2.In early-onset eclampsia,patients in the pre-eclampsia group have more severe liver function impairment.3.The most common self-perceived symptom of eclampsia patients with reversible leukoplasia in head imaging is visual disturbance,and headaches are the most common symptoms of cerebral infarction.